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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITGB5 All Species: 23.94
Human Site: T61 Identified Species: 47.88
UniProt: P18084 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18084 NP_002204.2 799 88054 T61 F G S P R S I T S R C D L R A
Chimpanzee Pan troglodytes XP_516706 899 98662 T161 F G S P R S I T S R C D L R A
Rhesus Macaque Macaca mulatta XP_001113909 799 87949 T61 F G S P R S I T S R C D L R A
Dog Lupus familis XP_851245 819 89576 T80 F G S L R S V T S R C D L K A
Cat Felis silvestris
Mouse Mus musculus O70309 798 87890 T61 F G N P R S I T S R C D L K A
Rat Rattus norvegicus Q6AYF4 787 85940 G56 F T H L S G A G E R C D T P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512659 789 86367 G56 F T H S S G I G E R C D T P G
Chicken Gallus gallus P07228 803 88535 T64 F L Q E G E P T S A R C D D L
Frog Xenopus laevis P12606 798 88149 T61 F L Q E G E P T S A R C D D L
Zebra Danio Brachydanio rerio NP_001076305 823 91335 T86 F G Q A R T L T S R C D F S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11584 846 92638 S112 L A A G G G G S A M S G S S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27874 809 90119 D78 K K P Y A R C D S R A K L M E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.3 98.6 86.4 N.A. 91.4 48 N.A. 47.1 42.7 43 68.8 N.A. 38 N.A. 38.4 N.A.
Protein Similarity: 100 88.6 99.5 90.8 N.A. 95.9 64.8 N.A. 64.7 59.6 60.3 79.9 N.A. 54.2 N.A. 54.6 N.A.
P-Site Identity: 100 100 100 80 N.A. 86.6 26.6 N.A. 33.3 20 20 53.3 N.A. 0 N.A. 20 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 26.6 N.A. 33.3 20 20 66.6 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 9 0 9 0 9 17 9 0 0 0 42 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 67 17 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 0 0 0 67 17 17 0 % D
% Glu: 0 0 0 17 0 17 0 0 17 0 0 0 0 0 17 % E
% Phe: 84 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 50 0 9 25 25 9 17 0 0 0 9 0 0 9 % G
% His: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 42 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 0 0 0 0 0 0 0 0 0 9 0 17 0 % K
% Leu: 9 17 0 17 0 0 9 0 0 0 0 0 50 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 34 0 0 17 0 0 0 0 0 0 17 0 % P
% Gln: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 50 9 0 0 0 75 17 0 0 25 0 % R
% Ser: 0 0 34 9 17 42 0 9 75 0 9 0 9 17 9 % S
% Thr: 0 17 0 0 0 9 0 67 0 0 0 0 17 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _