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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARF4 All Species: 62.1
Human Site: S174 Identified Species: 85.39
UniProt: P18085 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18085 NP_001651.1 180 20511 S174 Y E G L D W L S N E L S K R _
Chimpanzee Pan troglodytes XP_520054 162 18449 Q156 C N R T W Y V Q A T C A T Q _
Rhesus Macaque Macaca mulatta XP_001103974 180 20437 S174 Y E G L D W L S N E L S K R _
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_031505 180 20378 S174 Y E G L D W L S N E L S K R _
Rat Rattus norvegicus P61751 180 20378 S174 Y E G L D W L S N E L S K R _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511094 180 20493 S174 Y E G L D W L S N E L S K R _
Chicken Gallus gallus P49702 180 20461 S174 Y D G L D W L S H E L S K R _
Frog Xenopus laevis P51644 180 20567 S174 Y E G L D W L S N E L S K R _
Zebra Danio Brachydanio rerio NP_956170 180 20354 S174 Y E G L D W L S N E L S K R _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40945 180 20598 S174 Y E G L D W L S A E L A K K _
Honey Bee Apis mellifera XP_393787 180 20403 S174 Y E G L D W L S N E L A K K _
Nematode Worm Caenorhab. elegans Q10943 181 20503 S174 Y E G L D W L S N Q L K N R S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002302788 181 20661 S174 Y E G L D W L S N N I A N K A
Maize Zea mays P49076 181 20642 S174 Y E G L D W L S S N I A T K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36397 181 20590 S174 Y E G L D W L S N N I A S K A
Baker's Yeast Sacchar. cerevisiae P19146 181 20639 S174 Y E G L E W L S N N L K N Q S
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S177 F E G L D W L S T E L K K K S
Conservation
Percent
Protein Identity: 100 88.8 98.8 N.A. N.A. 96.1 96.1 N.A. 96.1 88.8 95 92.7 N.A. 84.4 85 80.6 N.A.
Protein Similarity: 100 88.8 98.8 N.A. N.A. 97.7 97.7 N.A. 98.3 97.7 97.7 97.2 N.A. 91.1 92.2 87.8 N.A.
P-Site Identity: 100 0 100 N.A. N.A. 100 100 N.A. 100 85.7 100 100 N.A. 78.5 85.7 73.3 N.A.
P-Site Similarity: 100 28.5 100 N.A. N.A. 100 100 N.A. 100 100 100 100 N.A. 92.8 100 80 N.A.
Percent
Protein Identity: 80.1 80.6 N.A. 81.2 71.2 77.8
Protein Similarity: 88.9 88.9 N.A. 88.4 86.1 87.5
P-Site Identity: 60 53.3 N.A. 60 60 66.6
P-Site Similarity: 80 80 N.A. 80 73.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 0 36 0 0 12 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 6 0 0 89 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 89 0 0 6 0 0 0 0 65 0 0 0 0 0 % E
% Phe: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 95 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 18 65 36 0 % K
% Leu: 0 0 0 95 0 0 95 0 0 0 77 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 0 71 24 0 0 18 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 6 0 6 0 0 0 12 0 % Q
% Arg: 0 0 6 0 0 0 0 0 0 0 0 0 0 53 0 % R
% Ser: 0 0 0 0 0 0 0 95 6 0 0 48 6 0 24 % S
% Thr: 0 0 0 6 0 0 0 0 6 6 0 0 12 0 0 % T
% Val: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 6 95 0 0 0 0 0 0 0 0 0 % W
% Tyr: 89 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 % _