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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARF4
All Species:
56.36
Human Site:
Y154
Identified Species:
77.5
UniProt:
P18085
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18085
NP_001651.1
180
20511
Y154
S
L
R
N
R
T
W
Y
V
Q
A
T
C
A
T
Chimpanzee
Pan troglodytes
XP_520054
162
18449
I136
D
L
P
N
A
M
A
I
S
E
M
T
D
K
L
Rhesus Macaque
Macaca mulatta
XP_001103974
180
20437
Y154
S
L
R
N
R
T
W
Y
V
Q
A
T
C
A
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_031505
180
20378
Y154
S
L
R
N
R
T
W
Y
V
Q
A
T
C
A
T
Rat
Rattus norvegicus
P61751
180
20378
Y154
S
L
R
N
R
T
W
Y
V
Q
A
T
C
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511094
180
20493
Y154
A
L
R
N
R
T
W
Y
V
Q
A
T
C
A
T
Chicken
Gallus gallus
P49702
180
20461
Y154
A
L
R
S
R
T
W
Y
V
Q
A
T
C
A
T
Frog
Xenopus laevis
P51644
180
20567
Y154
T
L
R
N
R
T
W
Y
V
Q
A
T
C
A
T
Zebra Danio
Brachydanio rerio
NP_956170
180
20354
Y154
S
L
R
S
R
T
W
Y
V
Q
A
T
C
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40945
180
20598
F154
Q
L
R
N
R
H
W
F
I
Q
S
T
C
A
T
Honey Bee
Apis mellifera
XP_393787
180
20403
Y154
S
L
R
G
R
H
W
Y
I
Q
S
T
C
A
T
Nematode Worm
Caenorhab. elegans
Q10943
181
20503
Y154
S
L
R
N
R
S
W
Y
I
Q
A
T
C
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302788
181
20661
Y154
S
L
R
Q
R
H
W
Y
I
Q
S
T
C
A
T
Maize
Zea mays
P49076
181
20642
Y154
S
L
R
Q
R
H
W
Y
I
Q
S
T
C
A
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P36397
181
20590
Y154
S
L
R
Q
R
H
W
Y
I
Q
S
T
C
A
T
Baker's Yeast
Sacchar. cerevisiae
P19146
181
20639
F154
S
I
R
N
R
P
W
F
I
Q
S
T
C
A
T
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
Y157
S
L
R
Q
R
S
W
Y
I
Q
A
T
C
A
T
Conservation
Percent
Protein Identity:
100
88.8
98.8
N.A.
N.A.
96.1
96.1
N.A.
96.1
88.8
95
92.7
N.A.
84.4
85
80.6
N.A.
Protein Similarity:
100
88.8
98.8
N.A.
N.A.
97.7
97.7
N.A.
98.3
97.7
97.7
97.2
N.A.
91.1
92.2
87.8
N.A.
P-Site Identity:
100
20
100
N.A.
N.A.
100
100
N.A.
93.3
86.6
93.3
93.3
N.A.
66.6
73.3
86.6
N.A.
P-Site Similarity:
100
26.6
100
N.A.
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
86.6
100
N.A.
Percent
Protein Identity:
80.1
80.6
N.A.
81.2
71.2
77.8
Protein Similarity:
88.9
88.9
N.A.
88.4
86.1
87.5
P-Site Identity:
73.3
73.3
N.A.
73.3
66.6
80
P-Site Similarity:
86.6
86.6
N.A.
86.6
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
6
0
6
0
0
0
59
0
0
95
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
95
0
0
% C
% Asp:
6
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
0
0
0
0
6
48
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% K
% Leu:
0
95
0
0
0
0
0
0
0
0
0
0
0
0
6
% L
% Met:
0
0
0
0
0
6
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
0
24
0
0
0
0
0
95
0
0
0
0
0
% Q
% Arg:
0
0
95
0
95
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
71
0
0
12
0
12
0
0
6
0
36
0
0
0
0
% S
% Thr:
6
0
0
0
0
48
0
0
0
0
0
100
0
0
95
% T
% Val:
0
0
0
0
0
0
0
0
48
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
95
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
83
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _