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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2B
All Species:
23.33
Human Site:
S292
Identified Species:
42.78
UniProt:
P18089
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18089
NP_000673.2
450
49954
S292
K
E
G
V
C
G
A
S
P
E
D
E
A
E
E
Chimpanzee
Pan troglodytes
XP_515627
843
90504
S687
K
E
D
V
C
G
A
S
P
E
D
E
A
E
E
Rhesus Macaque
Macaca mulatta
XP_001082230
445
49417
S292
K
E
G
V
C
G
A
S
P
E
D
E
A
E
E
Dog
Lupus familis
XP_854447
444
49208
S290
K
E
G
V
C
G
A
S
P
E
E
E
A
E
M
Cat
Felis silvestris
Mouse
Mus musculus
P30545
450
50154
T295
K
K
G
T
S
G
A
T
A
E
K
G
A
E
E
Rat
Rattus norvegicus
P19328
453
50351
T298
K
K
G
T
S
G
A
T
A
E
E
G
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514931
210
22727
T93
R
I
K
A
A
I
L
T
V
W
L
I
A
A
F
Chicken
Gallus gallus
XP_426355
614
69002
S489
Q
S
F
S
Y
S
Y
S
S
K
H
S
S
S
R
Frog
Xenopus laevis
P24628
442
49720
S306
Q
L
A
V
P
A
T
S
N
Q
C
K
N
A
S
Zebra Danio
Brachydanio rerio
Q90WY5
510
55953
N340
E
K
K
K
K
K
N
N
K
N
K
N
K
K
E
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
Q296
S
L
D
I
I
E
V
Q
S
N
S
R
C
N
L
Fruit Fly
Dros. melanogaster
P22270
601
64656
V472
D
P
K
G
C
I
Q
V
C
V
T
Q
A
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
T332
P
H
S
P
S
E
N
T
L
H
P
P
S
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
96.2
90
N.A.
83.1
83.6
N.A.
40
25.8
30.8
50.9
31.5
28.4
N.A.
N.A.
33.7
Protein Similarity:
100
51.2
96.8
93.1
N.A.
88.4
89.4
N.A.
41.7
36.8
53.1
62.1
51.3
42.5
N.A.
N.A.
51.8
P-Site Identity:
100
93.3
100
86.6
N.A.
53.3
46.6
N.A.
6.6
6.6
13.3
6.6
0
20
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
66.6
66.6
N.A.
20
26.6
33.3
33.3
6.6
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
47
0
16
0
0
0
54
16
0
% A
% Cys:
0
0
0
0
39
0
0
0
8
0
8
0
8
0
0
% C
% Asp:
8
0
16
0
0
0
0
0
0
0
24
0
8
8
0
% D
% Glu:
8
31
0
0
0
16
0
0
0
47
16
31
0
47
54
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
39
8
0
47
0
0
0
0
0
16
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
8
0
8
8
16
0
0
0
0
0
8
0
8
0
% I
% Lys:
47
24
24
8
8
8
0
0
8
8
16
8
8
8
0
% K
% Leu:
0
16
0
0
0
0
8
0
8
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
16
8
8
16
0
8
8
8
0
% N
% Pro:
8
8
0
8
8
0
0
0
31
0
8
8
0
0
0
% P
% Gln:
16
0
0
0
0
0
8
8
0
8
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
8
8
8
8
24
8
0
47
16
0
8
8
16
8
8
% S
% Thr:
0
0
0
16
0
0
8
31
0
0
8
0
0
0
8
% T
% Val:
0
0
0
39
0
0
8
8
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _