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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2B
All Species:
13.94
Human Site:
S324
Identified Species:
25.56
UniProt:
P18089
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18089
NP_000673.2
450
49954
S324
V
S
P
A
S
A
C
S
P
P
L
Q
Q
P
Q
Chimpanzee
Pan troglodytes
XP_515627
843
90504
S717
V
S
P
A
S
A
C
S
P
P
L
Q
Q
P
Q
Rhesus Macaque
Macaca mulatta
XP_001082230
445
49417
S319
V
S
A
A
S
A
C
S
P
P
L
Q
Q
P
Q
Dog
Lupus familis
XP_854447
444
49208
S318
A
S
P
A
A
A
C
S
P
P
L
R
Q
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P30545
450
50154
N324
A
S
P
A
S
V
F
N
P
P
L
Q
Q
P
Q
Rat
Rattus norvegicus
P19328
453
50351
N327
A
S
P
A
S
V
C
N
P
P
L
Q
Q
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514931
210
22727
P114
V
Y
K
G
D
K
G
P
R
V
P
G
R
P
Q
Chicken
Gallus gallus
XP_426355
614
69002
Y510
R
S
M
E
F
F
S
Y
R
R
R
R
K
R
S
Frog
Xenopus laevis
P24628
442
49720
P330
K
A
E
K
N
G
H
P
K
D
S
T
K
P
A
Zebra Danio
Brachydanio rerio
Q90WY5
510
55953
H383
T
M
T
P
S
G
I
H
S
P
A
T
M
Q
K
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
N317
G
T
V
P
L
F
E
N
R
H
E
K
A
T
E
Fruit Fly
Dros. melanogaster
P22270
601
64656
G493
T
P
P
Q
S
S
T
G
V
A
A
V
S
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
H355
G
M
R
A
S
D
T
H
L
R
P
D
T
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
96.2
90
N.A.
83.1
83.6
N.A.
40
25.8
30.8
50.9
31.5
28.4
N.A.
N.A.
33.7
Protein Similarity:
100
51.2
96.8
93.1
N.A.
88.4
89.4
N.A.
41.7
36.8
53.1
62.1
51.3
42.5
N.A.
N.A.
51.8
P-Site Identity:
100
100
93.3
80
N.A.
73.3
80
N.A.
20
6.6
6.6
13.3
0
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
86.6
N.A.
26.6
20
26.6
20
26.6
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
8
54
8
31
0
0
0
8
16
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
8
8
0
0
8
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
8
16
8
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
8
0
16
8
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
16
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
8
0
8
0
0
8
0
0
8
16
0
8
% K
% Leu:
0
0
0
0
8
0
0
0
8
0
47
0
0
0
0
% L
% Met:
0
16
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
24
0
0
0
0
0
0
0
% N
% Pro:
0
8
47
16
0
0
0
16
47
54
16
0
0
70
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
39
47
8
62
% Q
% Arg:
8
0
8
0
0
0
0
0
24
16
8
16
8
8
0
% R
% Ser:
0
54
0
0
62
8
8
31
8
0
8
0
8
0
8
% S
% Thr:
16
8
8
0
0
0
16
0
0
0
0
16
8
8
8
% T
% Val:
31
0
8
0
0
16
0
0
8
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _