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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2B
All Species:
23.03
Human Site:
S8
Identified Species:
42.22
UniProt:
P18089
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18089
NP_000673.2
450
49954
S8
M
D
H
Q
D
P
Y
S
V
Q
A
T
A
A
I
Chimpanzee
Pan troglodytes
XP_515627
843
90504
A403
R
G
G
T
G
T
A
A
G
Q
L
G
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001082230
445
49417
S8
M
D
H
Q
D
P
Y
S
V
Q
A
T
A
A
I
Dog
Lupus familis
XP_854447
444
49208
S8
M
D
H
Q
E
P
Y
S
V
Q
A
T
A
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P30545
450
50154
S8
M
V
H
Q
E
P
Y
S
V
Q
A
T
A
A
I
Rat
Rattus norvegicus
P19328
453
50351
S13
M
D
H
Q
E
P
Y
S
V
Q
A
T
A
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514931
210
22727
Chicken
Gallus gallus
XP_426355
614
69002
S207
L
P
P
P
S
P
Y
S
P
A
A
V
A
S
L
Frog
Xenopus laevis
P24628
442
49720
Q24
T
N
G
T
A
V
D
Q
K
P
H
Y
N
Y
Y
Zebra Danio
Brachydanio rerio
Q90WY5
510
55953
S37
M
I
K
L
A
P
Y
S
P
E
A
T
A
A
F
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
R19
H
F
D
S
T
S
N
R
T
S
K
S
F
D
E
Fruit Fly
Dros. melanogaster
P22270
601
64656
P105
L
G
L
Q
L
A
V
P
E
W
E
A
L
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
G48
P
Y
P
P
S
G
Y
G
L
T
R
I
L
I
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
96.2
90
N.A.
83.1
83.6
N.A.
40
25.8
30.8
50.9
31.5
28.4
N.A.
N.A.
33.7
Protein Similarity:
100
51.2
96.8
93.1
N.A.
88.4
89.4
N.A.
41.7
36.8
53.1
62.1
51.3
42.5
N.A.
N.A.
51.8
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
93.3
N.A.
0
33.3
0
53.3
0
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
93.3
100
N.A.
0
53.3
6.6
60
6.6
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
8
8
0
8
54
8
54
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
31
8
0
16
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
24
0
0
0
8
8
8
0
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
16
16
0
8
8
0
8
8
0
0
8
0
0
0
% G
% His:
8
0
39
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
39
% I
% Lys:
0
0
8
0
0
0
0
0
8
0
8
0
8
0
0
% K
% Leu:
16
0
8
8
8
0
0
0
8
0
8
0
16
16
16
% L
% Met:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
16
16
0
54
0
8
16
8
0
0
0
0
0
% P
% Gln:
0
0
0
47
0
0
0
8
0
47
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
8
16
8
0
54
0
8
0
8
0
8
0
% S
% Thr:
8
0
0
16
8
8
0
0
8
8
0
47
0
0
8
% T
% Val:
0
8
0
0
0
8
8
0
39
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
62
0
0
0
0
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _