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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2B
All Species:
27.58
Human Site:
T364
Identified Species:
50.56
UniProt:
P18089
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18089
NP_000673.2
450
49954
T364
W
R
R
R
A
Q
L
T
R
E
K
R
F
T
F
Chimpanzee
Pan troglodytes
XP_515627
843
90504
T757
W
R
R
R
A
Q
L
T
R
E
K
R
F
T
F
Rhesus Macaque
Macaca mulatta
XP_001082230
445
49417
T359
W
R
R
R
A
Q
L
T
R
E
K
R
F
T
F
Dog
Lupus familis
XP_854447
444
49208
T358
W
R
R
R
A
Q
L
T
R
E
K
R
F
T
F
Cat
Felis silvestris
Mouse
Mus musculus
P30545
450
50154
S364
W
R
R
R
T
Q
L
S
R
E
K
R
F
T
F
Rat
Rattus norvegicus
P19328
453
50351
S367
W
R
R
R
T
Q
L
S
R
E
K
R
F
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514931
210
22727
C143
I
G
S
F
F
A
P
C
L
I
M
I
L
V
Y
Chicken
Gallus gallus
XP_426355
614
69002
V539
F
T
F
V
L
A
V
V
M
G
V
F
V
V
C
Frog
Xenopus laevis
P24628
442
49720
H365
S
K
K
K
L
S
Q
H
K
E
K
K
A
T
Q
Zebra Danio
Brachydanio rerio
Q90WY5
510
55953
N424
A
R
R
K
A
M
V
N
R
E
K
R
F
T
F
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
G346
K
T
L
G
I
I
M
G
T
F
I
L
C
W
L
Fruit Fly
Dros. melanogaster
P22270
601
64656
S522
E
K
Q
K
I
S
L
S
K
E
R
R
A
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
S385
Q
K
R
R
L
A
Q
S
R
D
R
R
A
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
96.2
90
N.A.
83.1
83.6
N.A.
40
25.8
30.8
50.9
31.5
28.4
N.A.
N.A.
33.7
Protein Similarity:
100
51.2
96.8
93.1
N.A.
88.4
89.4
N.A.
41.7
36.8
53.1
62.1
51.3
42.5
N.A.
N.A.
51.8
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
0
0
20
66.6
0
20
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
13.3
53.3
80
6.6
60
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
39
24
0
0
0
0
0
0
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% E
% Phe:
8
0
8
8
8
0
0
0
0
8
0
8
54
0
54
% F
% Gly:
0
8
0
8
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
16
8
0
0
0
8
8
8
0
0
8
% I
% Lys:
8
24
8
24
0
0
0
0
16
0
62
8
0
0
0
% K
% Leu:
0
0
8
0
24
0
54
0
8
0
0
8
8
0
8
% L
% Met:
0
0
0
0
0
8
8
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
47
16
0
0
0
0
0
0
0
8
% Q
% Arg:
0
54
62
54
0
0
0
0
62
0
16
70
0
0
8
% R
% Ser:
8
0
8
0
0
16
0
31
0
0
0
0
0
0
0
% S
% Thr:
0
16
0
0
16
0
0
31
8
0
0
0
0
70
0
% T
% Val:
0
0
0
8
0
0
16
8
0
0
8
0
8
16
0
% V
% Trp:
47
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _