KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2B
All Species:
25.76
Human Site:
Y150
Identified Species:
47.22
UniProt:
P18089
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18089
NP_000673.2
450
49954
Y150
I
S
L
P
P
L
I
Y
K
G
D
Q
G
P
Q
Chimpanzee
Pan troglodytes
XP_515627
843
90504
Y545
I
S
L
P
P
L
I
Y
K
G
D
Q
G
P
Q
Rhesus Macaque
Macaca mulatta
XP_001082230
445
49417
Y150
I
S
L
P
P
L
I
Y
K
G
D
Q
G
P
Q
Dog
Lupus familis
XP_854447
444
49208
Y150
I
S
L
P
P
L
I
Y
K
G
D
Q
G
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P30545
450
50154
Y150
I
S
L
P
P
L
I
Y
K
G
D
Q
R
P
E
Rat
Rattus norvegicus
P19328
453
50351
Y155
I
S
L
P
P
L
I
Y
K
G
D
Q
R
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514931
210
22727
Chicken
Gallus gallus
XP_426355
614
69002
S349
I
S
F
P
P
L
I
S
M
Y
R
D
P
E
G
Frog
Xenopus laevis
P24628
442
49720
F166
A
I
S
C
P
L
L
F
G
L
N
N
T
G
S
Zebra Danio
Brachydanio rerio
Q90WY5
510
55953
S179
I
S
F
P
P
L
L
S
M
N
K
N
K
G
G
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
G161
I
S
V
T
W
L
V
G
F
S
I
S
I
P
P
Fruit Fly
Dros. melanogaster
P22270
601
64656
G247
I
S
S
P
P
L
I
G
W
N
D
W
P
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
G190
I
S
V
P
P
L
F
G
W
R
S
E
I
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
96.2
90
N.A.
83.1
83.6
N.A.
40
25.8
30.8
50.9
31.5
28.4
N.A.
N.A.
33.7
Protein Similarity:
100
51.2
96.8
93.1
N.A.
88.4
89.4
N.A.
41.7
36.8
53.1
62.1
51.3
42.5
N.A.
N.A.
51.8
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
0
40
13.3
33.3
26.6
46.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
40
33.3
40
40
53.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
54
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
24
% E
% Phe:
0
0
16
0
0
0
8
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
24
8
47
0
0
31
16
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
85
8
0
0
0
0
62
0
0
0
8
0
16
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
47
0
8
0
8
8
0
% K
% Leu:
0
0
47
0
0
93
16
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
16
8
16
0
0
0
% N
% Pro:
0
0
0
77
85
0
0
0
0
0
0
0
16
54
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
31
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
8
0
16
0
0
% R
% Ser:
0
85
16
0
0
0
0
16
0
8
8
8
0
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
16
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _