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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2B
All Species:
26.97
Human Site:
Y77
Identified Species:
49.44
UniProt:
P18089
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18089
NP_000673.2
450
49954
Y77
L
A
N
E
L
L
G
Y
W
Y
F
R
R
T
W
Chimpanzee
Pan troglodytes
XP_515627
843
90504
Y472
G
S
A
V
V
H
G
Y
W
D
F
R
C
T
W
Rhesus Macaque
Macaca mulatta
XP_001082230
445
49417
Y77
L
A
N
E
L
L
G
Y
W
Y
F
W
R
T
W
Dog
Lupus familis
XP_854447
444
49208
Y77
L
A
N
E
L
L
G
Y
W
Y
F
R
R
T
W
Cat
Felis silvestris
Mouse
Mus musculus
P30545
450
50154
Y77
L
A
N
E
L
L
G
Y
W
Y
F
W
R
A
W
Rat
Rattus norvegicus
P19328
453
50351
Y82
L
A
N
E
L
L
G
Y
W
Y
F
W
R
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514931
210
22727
Chicken
Gallus gallus
XP_426355
614
69002
Y276
L
A
N
E
L
M
N
Y
W
Y
F
G
K
V
W
Frog
Xenopus laevis
P24628
442
49720
E93
V
Y
M
E
V
V
G
E
W
R
F
S
R
I
H
Zebra Danio
Brachydanio rerio
Q90WY5
510
55953
Y106
L
A
N
E
L
M
G
Y
W
Y
F
R
S
V
W
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
P88
M
V
S
V
L
V
L
P
M
A
A
L
Y
Q
V
Fruit Fly
Dros. melanogaster
P22270
601
64656
R174
V
A
Y
S
I
L
G
R
W
E
F
G
I
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
H117
V
V
N
E
M
L
G
H
W
I
F
G
N
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
96.2
90
N.A.
83.1
83.6
N.A.
40
25.8
30.8
50.9
31.5
28.4
N.A.
N.A.
33.7
Protein Similarity:
100
51.2
96.8
93.1
N.A.
88.4
89.4
N.A.
41.7
36.8
53.1
62.1
51.3
42.5
N.A.
N.A.
51.8
P-Site Identity:
100
46.6
93.3
100
N.A.
86.6
86.6
N.A.
0
66.6
33.3
80
6.6
33.3
N.A.
N.A.
40
P-Site Similarity:
100
60
93.3
100
N.A.
86.6
86.6
N.A.
0
80
53.3
86.6
26.6
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
8
0
0
0
0
0
0
8
8
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
70
0
0
0
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
85
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
77
0
0
0
0
24
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
16
8
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
0
8
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
54
0
0
0
62
54
8
0
0
0
0
8
0
0
8
% L
% Met:
8
0
8
0
8
16
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
62
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
31
47
0
0
% R
% Ser:
0
8
8
8
0
0
0
0
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% T
% Val:
24
16
0
16
16
16
0
0
0
0
0
0
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
85
0
0
24
0
0
62
% W
% Tyr:
0
8
8
0
0
0
0
62
0
54
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _