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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 9.09
Human Site: S52 Identified Species: 40
UniProt: P18136 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18136 XP_002347049 129 14071 S52 A S Q S V S S S Y L A W Y Q Q
Chimpanzee Pan troglodytes XP_001141313 236 25781 S53 R A S Q G I S S W L A W Y Q Q
Rhesus Macaque Macaca mulatta XP_001089800 235 25361 S52 A S Q S V S S S L A W Y Q Q K
Dog Lupus familis XP_854722 117 12765 I41 S Q E E K V T I T C R A S Q S
Cat Felis silvestris
Mouse Mus musculus P01633 149 16415 T72 K A S Q D V S T T V A W Y Q Q
Rat Rattus norvegicus XP_002726184 159 17234 N57 L S S E Y Q G N Y L S W F Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.7 48.5 69.7 N.A. 52.3 47.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 44.4 51 79.8 N.A. 68.4 64.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 60 6.6 N.A. 40 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 73.3 26.6 N.A. 60 60 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 34 0 0 0 0 0 0 0 17 50 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 17 34 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % F
% Gly: 0 0 0 0 17 0 17 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 0 17 0 0 0 0 0 0 0 % I
% Lys: 17 0 0 0 17 0 0 0 0 0 0 0 0 0 17 % K
% Leu: 17 0 0 0 0 0 0 0 17 50 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 17 34 34 0 17 0 0 0 0 0 0 17 100 67 % Q
% Arg: 17 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % R
% Ser: 17 50 50 34 0 34 67 50 0 0 17 0 17 0 17 % S
% Thr: 0 0 0 0 0 0 17 17 34 0 0 0 0 0 0 % T
% Val: 0 0 0 0 34 34 0 0 0 17 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 17 0 17 67 0 0 0 % W
% Tyr: 0 0 0 0 17 0 0 0 34 0 0 17 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _