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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGR1
All Species:
16.97
Human Site:
T448
Identified Species:
41.48
UniProt:
P18146
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18146
NP_001955.1
543
57507
T448
S
Y
P
S
P
V
A
T
S
Y
P
S
P
V
T
Chimpanzee
Pan troglodytes
XP_517958
526
55748
S432
Y
P
S
P
V
A
T
S
Y
P
S
P
V
T
T
Rhesus Macaque
Macaca mulatta
XP_001107731
929
98911
T834
S
Y
P
S
P
V
A
T
S
Y
P
S
P
V
T
Dog
Lupus familis
XP_851238
542
57177
T447
S
Y
P
S
Q
V
A
T
S
Y
T
S
P
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P08046
533
56571
S439
P
A
A
S
S
L
S
S
Y
P
S
P
V
A
T
Rat
Rattus norvegicus
P08154
508
53916
S413
S
S
A
A
S
S
L
S
S
Y
P
S
P
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509408
291
31482
R197
G
H
K
P
F
Q
C
R
I
C
M
R
S
F
S
Chicken
Gallus gallus
O73691
194
21289
S100
S
S
V
A
A
Y
S
S
S
V
A
T
S
Y
S
Frog
Xenopus laevis
Q08427
421
46362
F327
C
R
I
C
M
R
N
F
S
R
S
D
H
L
T
Zebra Danio
Brachydanio rerio
P26632
511
55121
S417
S
V
S
N
I
S
I
S
A
S
S
P
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
58
94.2
N.A.
91.7
86.3
N.A.
34
27.4
39.9
61.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.4
58.2
95.5
N.A.
94.2
88.7
N.A.
39.7
30.7
49.1
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
13.3
46.6
N.A.
0
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
86.6
N.A.
33.3
60
N.A.
13.3
46.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
20
10
10
30
0
10
0
10
0
0
10
10
% A
% Cys:
10
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
10
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
30
20
20
0
0
0
0
20
30
30
40
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
10
0
10
0
10
0
0
0
% R
% Ser:
60
20
20
40
20
20
20
50
60
10
40
40
20
10
30
% S
% Thr:
0
0
0
0
0
0
10
30
0
0
10
10
0
10
60
% T
% Val:
0
10
10
0
10
30
0
0
0
10
0
0
30
40
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
30
0
0
0
10
0
0
20
40
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _