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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPX2
All Species:
13.64
Human Site:
Y125
Identified Species:
33.33
UniProt:
P18283
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18283
NP_002074.2
190
21954
Y125
Y
L
K
D
K
L
P
Y
P
Y
D
D
P
F
S
Chimpanzee
Pan troglodytes
Q0EFA0
201
21781
A133
F
L
R
E
A
L
P
A
P
S
D
D
A
T
A
Rhesus Macaque
Macaca mulatta
NP_001108609
190
21687
Y125
Y
L
K
D
K
L
P
Y
P
H
D
D
P
F
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHC0
190
21821
Y125
Y
L
K
D
K
L
P
Y
P
Y
D
D
P
F
S
Rat
Rattus norvegicus
P83645
190
21845
Y125
Y
L
K
D
K
L
P
Y
P
Y
D
D
P
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001156704
219
24474
P156
F
L
K
N
S
C
P
P
V
A
E
E
F
G
N
Frog
Xenopus laevis
NP_001088896
143
16617
I92
L
M
Q
D
P
K
S
I
I
W
S
P
V
R
R
Zebra Danio
Brachydanio rerio
NP_001007282
191
21595
Q126
F
L
K
E
K
L
P
Q
P
S
D
D
P
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95003
224
25537
E156
P
L
Y
E
F
V
K
E
S
C
P
Q
T
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48646
232
25566
K172
K
V
D
V
N
G
D
K
A
A
P
V
Y
K
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.6
98.4
N.A.
N.A.
94.2
93.6
N.A.
N.A.
38.3
48.4
66.4
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
100
74.1
98.9
N.A.
N.A.
97.3
97.3
N.A.
N.A.
50.6
59.4
80.6
N.A.
N.A.
N.A.
53.1
N.A.
P-Site Identity:
100
40
93.3
N.A.
N.A.
100
100
N.A.
N.A.
20
6.6
66.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
66.6
100
N.A.
N.A.
100
100
N.A.
N.A.
53.3
26.6
80
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
20
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
10
50
0
0
10
0
0
0
60
60
0
0
10
% D
% Glu:
0
0
0
30
0
0
0
10
0
0
10
10
0
0
0
% E
% Phe:
30
0
0
0
10
0
0
0
0
0
0
0
10
40
10
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
10
0
60
0
50
10
10
10
0
0
0
0
0
10
0
% K
% Leu:
10
80
0
0
0
60
0
0
0
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
10
0
70
10
60
0
20
10
50
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% R
% Ser:
0
0
0
0
10
0
10
0
10
20
10
0
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% T
% Val:
0
10
0
10
0
10
0
0
10
0
0
10
10
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
40
0
10
0
0
0
0
40
0
30
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _