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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRD5A1
All Species:
4.55
Human Site:
S73
Identified Species:
12.5
UniProt:
P18405
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18405
NP_001038.1
259
29459
S73
L
P
L
Y
Q
Y
A
S
E
S
A
P
R
L
R
Chimpanzee
Pan troglodytes
XP_001144414
211
24056
L31
G
C
A
V
F
P
R
L
R
S
A
P
N
C
I
Rhesus Macaque
Macaca mulatta
XP_001083405
263
30000
S77
L
P
L
Y
Q
Y
A
S
E
S
A
P
R
L
R
Dog
Lupus familis
XP_535799
255
29053
R69
V
P
L
W
V
C
A
R
T
A
A
E
R
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q68FF9
255
29326
R69
W
P
L
Y
E
C
I
R
P
A
A
A
R
L
G
Rat
Rattus norvegicus
P24008
259
29762
R73
W
P
L
Y
E
Y
I
R
P
A
A
A
R
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509315
164
18777
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8AVI9
319
36573
Q110
V
P
V
P
E
W
L
Q
A
V
L
Q
F
L
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38944
262
30616
L75
F
P
F
G
R
H
A
L
N
P
K
S
L
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
92
71.4
N.A.
61
60.2
N.A.
37.4
N.A.
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81.4
94.3
78.7
N.A.
73.3
72.9
N.A.
47.4
N.A.
38.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
46.6
N.A.
40
46.6
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
66.6
N.A.
53.3
60
N.A.
0
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
45
0
12
34
67
23
0
0
0
% A
% Cys:
0
12
0
0
0
23
0
0
0
0
0
0
0
12
12
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
34
0
0
0
23
0
0
12
0
0
0
% E
% Phe:
12
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
23
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
23
0
56
0
0
0
12
23
0
0
12
0
12
78
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% N
% Pro:
0
78
0
12
0
12
0
0
23
12
0
34
0
0
0
% P
% Gln:
0
0
0
0
23
0
0
12
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
12
0
12
34
12
0
0
0
56
0
34
% R
% Ser:
0
0
0
0
0
0
0
23
0
34
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% T
% Val:
23
0
12
12
12
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
23
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
45
0
34
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _