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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRA
All Species:
17.27
Human Site:
S176
Identified Species:
38
UniProt:
P18433
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18433
NP_002827.1
802
90600
S176
K
K
Y
K
Q
A
G
S
H
S
N
S
K
Q
A
Chimpanzee
Pan troglodytes
XP_001158332
793
89670
S176
K
K
Y
K
Q
A
G
S
H
S
N
S
F
R
L
Rhesus Macaque
Macaca mulatta
XP_001114682
793
89729
S176
K
K
Y
K
Q
A
G
S
H
S
N
S
F
R
L
Dog
Lupus familis
XP_534366
793
89602
S176
K
K
Y
K
Q
A
G
S
H
S
N
S
F
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P18052
829
93679
S176
K
K
Y
K
Q
A
G
S
H
S
N
S
F
R
L
Rat
Rattus norvegicus
Q03348
796
90242
Q176
L
R
F
K
K
Y
K
Q
A
G
S
H
S
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516836
648
74144
P58
D
M
E
P
Q
S
V
P
L
L
A
R
S
P
S
Chicken
Gallus gallus
Q6YI48
1434
161661
S327
E
I
E
Y
R
M
T
S
G
P
W
S
E
V
H
Frog
Xenopus laevis
NP_001089394
819
92510
R193
I
I
V
L
Y
M
L
R
F
K
K
Y
K
Q
A
Zebra Danio
Brachydanio rerio
A4IFW2
1909
213435
G447
E
P
N
G
Q
I
R
G
Y
R
I
Y
Y
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16621
2029
229038
N457
Y
K
V
Y
Y
T
T
N
S
N
Q
P
E
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.2
95
N.A.
91.5
93.3
N.A.
74.4
23.9
80.4
22.5
N.A.
20.3
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
98.2
96.6
N.A.
93.3
95.6
N.A.
77.4
36.4
87.1
31.3
N.A.
28.6
N.A.
N.A.
N.A.
P-Site Identity:
100
80
80
80
N.A.
80
6.6
N.A.
6.6
13.3
20
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
86.6
N.A.
86.6
40
N.A.
20
33.3
20
26.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
46
0
0
10
0
10
0
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
19
0
0
0
0
0
0
0
0
0
19
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
0
0
37
0
0
% F
% Gly:
0
0
0
10
0
0
46
10
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
46
0
0
10
0
0
10
% H
% Ile:
10
19
0
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
46
55
0
55
10
0
10
0
0
10
10
0
19
0
0
% K
% Leu:
10
0
0
10
0
0
10
0
10
10
0
0
0
0
37
% L
% Met:
0
10
0
0
0
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
10
46
0
0
10
0
% N
% Pro:
0
10
0
10
0
0
0
10
0
10
0
10
0
10
0
% P
% Gln:
0
0
0
0
64
0
0
10
0
0
10
0
0
19
0
% Q
% Arg:
0
10
0
0
10
0
10
10
0
10
0
10
0
37
0
% R
% Ser:
0
0
0
0
0
10
0
55
10
46
10
55
19
0
37
% S
% Thr:
0
0
0
0
0
10
19
0
0
0
0
0
0
10
0
% T
% Val:
0
0
19
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
46
19
19
10
0
0
10
0
0
19
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _