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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GABRB1
All Species:
9.09
Human Site:
S381
Identified Species:
20
UniProt:
P18505
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18505
NP_000803.2
474
54235
S381
I
R
N
E
T
S
G
S
E
V
L
T
S
V
S
Chimpanzee
Pan troglodytes
XP_001154327
441
50537
E349
R
N
E
T
S
G
S
E
V
L
T
S
V
S
D
Rhesus Macaque
Macaca mulatta
XP_001099985
424
48499
E332
R
N
E
T
S
G
S
E
V
L
T
S
V
S
D
Dog
Lupus familis
XP_867140
476
54815
E383
K
N
E
M
A
T
S
E
A
V
M
G
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P50571
474
54082
S381
I
R
N
E
T
S
G
S
E
V
L
T
G
V
S
Rat
Rattus norvegicus
P15431
474
54054
S381
I
R
N
E
T
S
G
S
E
V
L
T
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505751
512
59057
E419
K
N
E
M
A
T
S
E
A
V
M
G
L
G
D
Chicken
Gallus gallus
P19019
476
54414
V383
N
E
V
A
S
N
E
V
T
T
S
V
T
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695300
471
53878
V378
T
L
E
I
H
N
E
V
A
G
N
E
I
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08832
496
56579
L402
R
G
T
Y
N
A
T
L
D
S
I
G
T
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O18276
550
62439
Y454
E
S
P
D
Y
P
R
Y
S
T
T
S
L
K
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
89
78.9
N.A.
98
98.3
N.A.
72.6
78.5
N.A.
78.2
N.A.
46.5
N.A.
41
N.A.
Protein Similarity:
100
93
89
88.6
N.A.
98.9
98.9
N.A.
82.8
88
N.A.
89.2
N.A.
63
N.A.
58.5
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
93.3
93.3
N.A.
6.6
0
N.A.
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
20
20
20
N.A.
93.3
93.3
N.A.
20
26.6
N.A.
13.3
N.A.
33.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
19
10
0
0
28
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
10
37
% D
% Glu:
10
10
46
28
0
0
19
37
28
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
19
28
0
0
10
0
28
19
19
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
28
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
19
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
0
0
0
0
0
10
0
19
28
0
28
0
0
% L
% Met:
0
0
0
19
0
0
0
0
0
0
19
0
0
0
0
% M
% Asn:
10
37
28
0
10
19
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
28
28
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
28
28
37
28
10
10
10
28
10
19
28
% S
% Thr:
10
0
10
19
28
19
10
0
10
19
28
28
19
10
19
% T
% Val:
0
0
10
0
0
0
0
19
19
46
0
10
19
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _