Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL1RN All Species: 6.36
Human Site: S32 Identified Species: 20
UniProt: P18510 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18510 NP_000568.1 177 20055 S32 C R P S G R K S S K M Q A F R
Chimpanzee Pan troglodytes XP_001147954 177 20052 S32 C R P S G R K S S K M Q A F R
Rhesus Macaque Macaca mulatta P48090 269 30462 D111 F L D T R N N D A C V H D A P
Dog Lupus familis XP_854686 155 16963 G29 H D N Q L L A G G L H A G K V
Cat Felis silvestris
Mouse Mus musculus P25085 178 20256 P33 C R P S G K R P C K M Q A F R
Rat Rattus norvegicus P25086 178 20264 P33 G H P A G K R P C K M Q A F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521241 184 21101 Q34 A F R L T K M Q S K R P V Y R
Chicken Gallus gallus NP_989855 267 29804 Y111 A G A P A F R Y T R S Q S F D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 21.9 34.4 N.A. 75.8 73.5 N.A. 58.1 28.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 36 51.9 N.A. 88.7 85.3 N.A. 68.4 42.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. 73.3 53.3 N.A. 20 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 0 N.A. 86.6 73.3 N.A. 33.3 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 13 13 13 0 13 0 13 0 0 13 50 13 0 % A
% Cys: 38 0 0 0 0 0 0 0 25 13 0 0 0 0 0 % C
% Asp: 0 13 13 0 0 0 0 13 0 0 0 0 13 0 13 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 13 13 0 0 0 13 0 0 0 0 0 0 0 63 0 % F
% Gly: 13 13 0 0 50 0 0 13 13 0 0 0 13 0 0 % G
% His: 13 13 0 0 0 0 0 0 0 0 13 13 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 38 25 0 0 63 0 0 0 13 0 % K
% Leu: 0 13 0 13 13 13 0 0 0 13 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 50 0 0 0 0 % M
% Asn: 0 0 13 0 0 13 13 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 50 13 0 0 0 25 0 0 0 13 0 0 13 % P
% Gln: 0 0 0 13 0 0 0 13 0 0 0 63 0 0 0 % Q
% Arg: 0 38 13 0 13 25 38 0 0 13 13 0 0 0 63 % R
% Ser: 0 0 0 38 0 0 0 25 38 0 13 0 13 0 0 % S
% Thr: 0 0 0 13 13 0 0 0 13 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 13 0 13 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 13 0 0 0 0 0 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _