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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL1RN
All Species:
6.36
Human Site:
S32
Identified Species:
20
UniProt:
P18510
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18510
NP_000568.1
177
20055
S32
C
R
P
S
G
R
K
S
S
K
M
Q
A
F
R
Chimpanzee
Pan troglodytes
XP_001147954
177
20052
S32
C
R
P
S
G
R
K
S
S
K
M
Q
A
F
R
Rhesus Macaque
Macaca mulatta
P48090
269
30462
D111
F
L
D
T
R
N
N
D
A
C
V
H
D
A
P
Dog
Lupus familis
XP_854686
155
16963
G29
H
D
N
Q
L
L
A
G
G
L
H
A
G
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P25085
178
20256
P33
C
R
P
S
G
K
R
P
C
K
M
Q
A
F
R
Rat
Rattus norvegicus
P25086
178
20264
P33
G
H
P
A
G
K
R
P
C
K
M
Q
A
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521241
184
21101
Q34
A
F
R
L
T
K
M
Q
S
K
R
P
V
Y
R
Chicken
Gallus gallus
NP_989855
267
29804
Y111
A
G
A
P
A
F
R
Y
T
R
S
Q
S
F
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
21.9
34.4
N.A.
75.8
73.5
N.A.
58.1
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
36
51.9
N.A.
88.7
85.3
N.A.
68.4
42.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
73.3
53.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
0
N.A.
86.6
73.3
N.A.
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
13
13
13
0
13
0
13
0
0
13
50
13
0
% A
% Cys:
38
0
0
0
0
0
0
0
25
13
0
0
0
0
0
% C
% Asp:
0
13
13
0
0
0
0
13
0
0
0
0
13
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
13
13
0
0
0
13
0
0
0
0
0
0
0
63
0
% F
% Gly:
13
13
0
0
50
0
0
13
13
0
0
0
13
0
0
% G
% His:
13
13
0
0
0
0
0
0
0
0
13
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
38
25
0
0
63
0
0
0
13
0
% K
% Leu:
0
13
0
13
13
13
0
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
13
0
0
0
50
0
0
0
0
% M
% Asn:
0
0
13
0
0
13
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
50
13
0
0
0
25
0
0
0
13
0
0
13
% P
% Gln:
0
0
0
13
0
0
0
13
0
0
0
63
0
0
0
% Q
% Arg:
0
38
13
0
13
25
38
0
0
13
13
0
0
0
63
% R
% Ser:
0
0
0
38
0
0
0
25
38
0
13
0
13
0
0
% S
% Thr:
0
0
0
13
13
0
0
0
13
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _