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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITGB6 All Species: 31.82
Human Site: Y774 Identified Species: 63.64
UniProt: P18564 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18564 NP_000879.2 788 85936 Y774 S T F K N V T Y K H R E K Q K
Chimpanzee Pan troglodytes XP_001149096 788 85924 Y774 S T F K N V T Y K H R E K Q K
Rhesus Macaque Macaca mulatta XP_001094740 788 85915 Y774 S T F K N V T Y K H R E K Q K
Dog Lupus familis XP_545490 788 85908 Y774 S T F K N V T Y K H R E K Q K
Cat Felis silvestris
Mouse Mus musculus Q9Z0T9 787 86023 Y773 S T F K N V T Y K H R E K H K
Rat Rattus norvegicus Q6AYF4 787 85940 Y773 S T F K N V T Y K H R E K H K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512659 789 86367 Y774 S T F K N V T Y K H Q E K Q K
Chicken Gallus gallus P07228 803 88535 Y788 D T G E N P I Y K S A V T T V
Frog Xenopus laevis P12607 798 88285 S785 G E N P I Y K S A V A T V V N
Zebra Danio Brachydanio rerio XP_700725 782 85179 Y768 S T F K N V T Y K S T G Q Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11584 846 92638 Q833 G E N P I Y K Q A T S T F K N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27874 809 90119 Q794 N E N P I Y K Q A T T T F K N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.8 95.5 N.A. 90.4 90.7 N.A. 84.4 41.9 41.8 58.6 N.A. 36.1 N.A. 37 N.A.
Protein Similarity: 100 99.8 99.3 97 N.A. 95 95 N.A. 93 58.9 60.9 73.4 N.A. 54.4 N.A. 54.7 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 26.6 0 73.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 33.3 0 80 N.A. 6.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 25 0 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 25 0 9 0 0 0 0 0 0 0 59 0 0 0 % E
% Phe: 0 0 67 0 0 0 0 0 0 0 0 0 17 0 0 % F
% Gly: 17 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 59 0 0 0 17 0 % H
% Ile: 0 0 0 0 25 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 67 0 0 25 0 75 0 0 0 59 17 67 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 25 0 75 0 0 0 0 0 0 0 0 0 25 % N
% Pro: 0 0 0 25 0 9 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 17 0 0 9 0 9 50 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % R
% Ser: 67 0 0 0 0 0 0 9 0 17 9 0 0 0 0 % S
% Thr: 0 75 0 0 0 0 67 0 0 17 17 25 9 9 0 % T
% Val: 0 0 0 0 0 67 0 0 0 9 0 9 9 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 25 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _