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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHCE All Species: 8.79
Human Site: S73 Identified Species: 21.48
UniProt: P18577 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18577 NP_065231.2 417 45560 S73 T S N F R R H S W S S V A F N
Chimpanzee Pan troglodytes Q28813 417 45574 S73 T S S F R R H S W S S V A F S
Rhesus Macaque Macaca mulatta Q28849 417 45785 S73 T S N L R R N S W S S V A F N
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8CF94 418 45859 W73 S S F R R H S W S S V A F N L
Rat Rattus norvegicus O88298 422 46565 W73 S S F R R H G W S S V A F S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510671 498 54633 G74 M T F L K K Y G F S S V G F N
Chicken Gallus gallus Q6XL41 467 51669 G94 M T F L K R Y G F G A V G F N
Frog Xenopus laevis Q6DCG4 460 50248 G87 M T F L K R Y G F S S V A F N
Zebra Danio Brachydanio rerio Q7T070 459 50104 G83 M T F L Q R Y G F S S M G F N
Tiger Blowfish Takifugu rubipres Q18PF6 458 49646 G83 M T F L Q R Y G F G S V G F N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 78.4 N.A. N.A. 57.6 55.6 N.A. 28.5 29.9 33.9 32.6 31.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.2 85.6 N.A. N.A. 72 69.4 N.A. 47.5 49.2 51.2 50.5 48.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 86.6 N.A. N.A. 20 20 N.A. 33.3 26.6 46.6 33.3 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 N.A. N.A. 26.6 26.6 N.A. 66.6 60 73.3 66.6 60 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 20 40 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 70 20 0 0 0 0 50 0 0 0 20 80 10 % F
% Gly: 0 0 0 0 0 0 10 50 0 20 0 0 40 0 0 % G
% His: 0 0 0 0 0 20 20 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 30 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 60 0 0 0 0 0 0 0 0 0 0 10 % L
% Met: 50 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 20 0 0 0 10 0 0 0 0 0 0 10 70 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 20 50 70 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 50 10 0 0 0 10 30 20 80 70 0 0 10 10 % S
% Thr: 30 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 20 70 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 20 30 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _