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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHCE
All Species:
6.97
Human Site:
Y165
Identified Species:
17.04
UniProt:
P18577
Number Species:
9
Phosphosite Substitution
Charge Score:
0.56
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18577
NP_065231.2
417
45560
Y165
S
N
I
F
N
T
D
Y
H
M
N
L
R
H
F
Chimpanzee
Pan troglodytes
Q28813
417
45574
Y165
S
N
I
F
N
T
D
Y
H
M
N
L
M
H
I
Rhesus Macaque
Macaca mulatta
Q28849
417
45785
Y165
N
N
I
F
K
I
D
Y
G
M
N
M
M
H
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8CF94
418
45859
M168
K
M
T
E
H
I
I
M
M
H
G
H
V
F
G
Rat
Rattus norvegicus
O88298
422
46565
M172
R
I
E
D
H
I
I
M
M
Y
G
H
V
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510671
498
54633
D165
I
D
K
L
E
A
Q
D
I
G
A
S
M
I
I
Chicken
Gallus gallus
Q6XL41
467
51669
D186
L
N
L
L
H
V
K
D
A
G
G
S
M
T
I
Frog
Xenopus laevis
Q6DCG4
460
50248
D179
L
N
I
V
G
A
K
D
A
G
G
S
M
T
I
Zebra Danio
Brachydanio rerio
Q7T070
459
50104
D175
L
S
I
L
G
A
N
D
A
G
G
S
M
T
I
Tiger Blowfish
Takifugu rubipres
Q18PF6
458
49646
D175
L
S
L
L
G
T
K
D
A
G
G
S
M
T
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
78.4
N.A.
N.A.
57.6
55.6
N.A.
28.5
29.9
33.9
32.6
31.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.2
85.6
N.A.
N.A.
72
69.4
N.A.
47.5
49.2
51.2
50.5
48.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
53.3
N.A.
N.A.
0
0
N.A.
0
6.6
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
66.6
N.A.
N.A.
6.6
6.6
N.A.
6.6
20
13.3
20
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
30
0
0
40
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
30
50
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
30
0
0
0
0
0
0
0
0
0
20
10
% F
% Gly:
0
0
0
0
30
0
0
0
10
50
60
0
0
0
20
% G
% His:
0
0
0
0
30
0
0
0
20
10
0
20
0
30
0
% H
% Ile:
10
10
50
0
0
30
20
0
10
0
0
0
0
10
70
% I
% Lys:
10
0
10
0
10
0
30
0
0
0
0
0
0
0
0
% K
% Leu:
40
0
20
40
0
0
0
0
0
0
0
20
0
0
0
% L
% Met:
0
10
0
0
0
0
0
20
20
30
0
10
70
0
0
% M
% Asn:
10
50
0
0
20
0
10
0
0
0
30
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
20
20
0
0
0
0
0
0
0
0
0
50
0
0
0
% S
% Thr:
0
0
10
0
0
30
0
0
0
0
0
0
0
40
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _