KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDBP
All Species:
25.45
Human Site:
S124
Identified Species:
70
UniProt:
P18615
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18615
NP_002895.3
380
43240
S124
D
D
D
L
Q
E
S
S
R
R
P
Q
R
K
S
Chimpanzee
Pan troglodytes
XP_527349
377
42875
S119
D
D
D
L
Q
E
S
S
R
H
P
Q
R
K
S
Rhesus Macaque
Macaca mulatta
XP_001113859
380
43189
S124
D
D
D
L
Q
E
S
S
R
R
P
Q
R
K
S
Dog
Lupus familis
XP_532087
374
42309
S124
D
D
D
L
Q
E
S
S
R
R
P
Q
R
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P19426
375
42536
S124
D
E
D
L
Q
E
P
S
R
R
P
Q
R
K
S
Rat
Rattus norvegicus
NP_997713
369
41754
S124
D
E
D
L
Q
E
P
S
R
R
P
Q
R
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089853
335
38349
S124
D
E
E
Q
A
E
A
S
R
R
S
Q
R
K
S
Zebra Danio
Brachydanio rerio
NP_001002375
346
39718
A124
D
E
E
P
P
D
S
A
K
R
I
H
R
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92204
280
31792
D79
I
Q
K
Q
T
K
Q
D
Q
T
S
F
K
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.2
94.7
N.A.
91.5
91.3
N.A.
N.A.
N.A.
64.2
65.2
N.A.
29.2
N.A.
N.A.
N.A.
Protein Similarity:
100
98.1
100
97.3
N.A.
94.4
94.7
N.A.
N.A.
N.A.
76.3
76.8
N.A.
47.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
60
40
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
80
73.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
89
45
67
0
0
12
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
45
23
0
0
78
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
12
0
0
12
0
0
12
0
0
0
12
89
0
% K
% Leu:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
12
0
23
0
0
0
67
0
0
0
12
% P
% Gln:
0
12
0
23
67
0
12
0
12
0
0
78
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
78
78
0
0
89
12
0
% R
% Ser:
0
0
0
0
0
0
56
78
0
0
23
0
0
0
89
% S
% Thr:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _