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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDBP
All Species:
21.52
Human Site:
S185
Identified Species:
59.17
UniProt:
P18615
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18615
NP_002895.3
380
43240
S185
S
S
A
S
P
P
R
S
R
S
R
D
R
S
H
Chimpanzee
Pan troglodytes
XP_527349
377
42875
S180
S
S
A
S
P
P
R
S
C
S
R
D
R
S
H
Rhesus Macaque
Macaca mulatta
XP_001113859
380
43189
S185
S
S
A
S
P
P
R
S
R
S
R
D
R
S
H
Dog
Lupus familis
XP_532087
374
42309
S185
S
S
T
S
P
P
R
S
R
S
R
D
H
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P19426
375
42536
S185
S
S
A
S
P
P
R
S
R
S
R
D
R
S
H
Rat
Rattus norvegicus
NP_997713
369
41754
S185
S
S
A
S
P
P
R
S
R
S
R
D
R
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089853
335
38349
E175
D
R
E
P
F
D
R
E
R
G
R
E
R
D
R
Zebra Danio
Brachydanio rerio
NP_001002375
346
39718
G181
R
E
R
D
R
E
R
G
R
E
R
E
R
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92204
280
31792
R130
I
I
K
E
E
P
R
R
Q
N
L
Y
Q
H
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.2
94.7
N.A.
91.5
91.3
N.A.
N.A.
N.A.
64.2
65.2
N.A.
29.2
N.A.
N.A.
N.A.
Protein Similarity:
100
98.1
100
97.3
N.A.
94.4
94.7
N.A.
N.A.
N.A.
76.3
76.8
N.A.
47.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
100
100
N.A.
N.A.
N.A.
26.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
80
N.A.
100
100
N.A.
N.A.
N.A.
33.3
33.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
0
0
12
0
12
0
0
0
0
0
67
0
23
0
% D
% Glu:
0
12
12
12
12
12
0
12
0
12
0
23
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
56
% H
% Ile:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
12
67
78
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% Q
% Arg:
12
12
12
0
12
0
100
12
78
0
89
0
78
0
34
% R
% Ser:
67
67
0
67
0
0
0
67
0
67
0
0
0
67
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _