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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAG3 All Species: 15.15
Human Site: S484 Identified Species: 55.56
UniProt: P18627 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18627 NP_002277.4 525 57449 S484 Q W R P R R F S A L E Q G I H
Chimpanzee Pan troglodytes XP_508966 527 57737 S484 Q W R P R R F S A L E Q G I H
Rhesus Macaque Macaca mulatta XP_001108881 523 57136 S484 Q W R P R R F S A L E Q G I H
Dog Lupus familis XP_543847 392 41977 E372 K I G E L E Q E P E L E L E P
Cat Felis silvestris
Mouse Mus musculus Q61790 521 56959 S476 Q L L L R R F S A L E H G I Q
Rat Rattus norvegicus Q5BK54 525 57970 S476 Q L L R R R F S A L E H G I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519658 975 104604 E935 Q K Q W I Q V E P E E A G L W
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 92.3 56 N.A. 69.5 68.1 N.A. 20.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.2 93.7 60.3 N.A. 74.4 75.2 N.A. 30.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 66.6 66.6 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 66.6 66.6 N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 72 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 15 0 15 0 29 0 29 86 15 0 15 0 % E
% Phe: 0 0 0 0 0 0 72 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 0 0 0 0 0 0 86 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 43 % H
% Ile: 0 15 0 0 15 0 0 0 0 0 0 0 0 72 0 % I
% Lys: 15 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 29 29 15 15 0 0 0 0 72 15 0 15 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 43 0 0 0 0 29 0 0 0 0 0 15 % P
% Gln: 86 0 15 0 0 15 15 0 0 0 0 43 0 0 15 % Q
% Arg: 0 0 43 15 72 72 0 0 0 0 0 0 0 0 15 % R
% Ser: 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % V
% Trp: 0 43 0 15 0 0 0 0 0 0 0 0 0 0 15 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _