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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAG3
All Species:
15.15
Human Site:
S484
Identified Species:
55.56
UniProt:
P18627
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18627
NP_002277.4
525
57449
S484
Q
W
R
P
R
R
F
S
A
L
E
Q
G
I
H
Chimpanzee
Pan troglodytes
XP_508966
527
57737
S484
Q
W
R
P
R
R
F
S
A
L
E
Q
G
I
H
Rhesus Macaque
Macaca mulatta
XP_001108881
523
57136
S484
Q
W
R
P
R
R
F
S
A
L
E
Q
G
I
H
Dog
Lupus familis
XP_543847
392
41977
E372
K
I
G
E
L
E
Q
E
P
E
L
E
L
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61790
521
56959
S476
Q
L
L
L
R
R
F
S
A
L
E
H
G
I
Q
Rat
Rattus norvegicus
Q5BK54
525
57970
S476
Q
L
L
R
R
R
F
S
A
L
E
H
G
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519658
975
104604
E935
Q
K
Q
W
I
Q
V
E
P
E
E
A
G
L
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
92.3
56
N.A.
69.5
68.1
N.A.
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
93.7
60.3
N.A.
74.4
75.2
N.A.
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
66.6
66.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
66.6
66.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
72
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
15
0
15
0
29
0
29
86
15
0
15
0
% E
% Phe:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
0
86
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
43
% H
% Ile:
0
15
0
0
15
0
0
0
0
0
0
0
0
72
0
% I
% Lys:
15
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
29
29
15
15
0
0
0
0
72
15
0
15
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
43
0
0
0
0
29
0
0
0
0
0
15
% P
% Gln:
86
0
15
0
0
15
15
0
0
0
0
43
0
0
15
% Q
% Arg:
0
0
43
15
72
72
0
0
0
0
0
0
0
0
15
% R
% Ser:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% V
% Trp:
0
43
0
15
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _