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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC1 All Species: 26.36
Human Site: S288 Identified Species: 48.33
UniProt: P18754 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18754 NP_001041659.1 421 44969 S288 F I P Q N L T S F K N S T K S
Chimpanzee Pan troglodytes XP_001152659 421 44920 S288 F I P Q N L T S F K N S T K S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544458 630 67681 S497 F V P Q N L T S F K N S T K S
Cat Felis silvestris
Mouse Mus musculus Q8VE37 421 44912 S288 F I P Q N L T S F K N S T K S
Rat Rattus norvegicus NP_001121661 421 45093 S288 F I P Q N L T S F K N S T K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_427366 194 21051 R63 A A L T D D G R V F I W G S F
Frog Xenopus laevis P25183 424 45052 S293 Y A P Q N L T S F K N S T K S
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 L351 M V P R L V K L F D F P G R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25171 547 58832 P287 G K E F A L T P I K T E L K D
Honey Bee Apis mellifera XP_394158 439 46956 T301 F H P Q V S K T F S G K V W R
Nematode Worm Caenorhab. elegans Q18211 569 61466 N417 V G Q D G Q D N R E L R V F L
Sea Urchin Strong. purpuratus XP_001191815 424 45249 S293 F T P Q P I T S F N D V Q V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21827 482 52995 A337 V V I R S I A A G E H H S L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 64.7 N.A. 93.8 93.3 N.A. N.A. 37 75.9 22.2 N.A. 29 45.5 29.5 52.8
Protein Similarity: 100 99.7 N.A. 65.8 N.A. 96.9 96.6 N.A. N.A. 42 85.6 40 N.A. 43.6 63 42.5 70.7
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. N.A. 0 86.6 13.3 N.A. 26.6 26.6 0 40
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 6.6 93.3 40 N.A. 26.6 33.3 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 0 8 0 8 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 8 0 0 8 8 0 0 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 16 0 8 0 0 8 % E
% Phe: 54 0 0 8 0 0 0 0 70 8 8 0 0 8 8 % F
% Gly: 8 8 0 0 8 0 8 0 8 0 8 0 16 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 0 31 8 0 0 16 0 0 8 0 8 0 0 0 8 % I
% Lys: 0 8 0 0 0 0 16 0 0 54 0 8 0 54 0 % K
% Leu: 0 0 8 0 8 54 0 8 0 0 8 0 8 8 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 47 0 0 8 0 8 47 0 0 0 0 % N
% Pro: 0 0 70 0 8 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 0 0 8 62 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 16 0 0 0 8 8 0 0 8 0 8 8 % R
% Ser: 0 0 0 0 8 8 0 54 0 8 0 47 8 8 47 % S
% Thr: 0 8 0 8 0 0 62 8 0 0 8 0 47 0 0 % T
% Val: 16 24 0 0 8 8 0 0 8 0 0 8 16 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _