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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC1 All Species: 29.09
Human Site: S85 Identified Species: 53.33
UniProt: P18754 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18754 NP_001041659.1 421 44969 S85 H T V C L S K S G Q V Y S F G
Chimpanzee Pan troglodytes XP_001152659 421 44920 S85 H T V C L S K S G Q V Y S F G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544458 630 67681 S294 H T V C L S K S G Q V Y S F G
Cat Felis silvestris
Mouse Mus musculus Q8VE37 421 44912 S85 H T V C L S Q S G Q V Y S F G
Rat Rattus norvegicus NP_001121661 421 45093 S85 H T V C L S Q S G Q V Y S F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_427366 194 21051
Frog Xenopus laevis P25183 424 45052 S91 H T V C L G A S G S I Y T F G
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 E141 H S L I I T T E G K L W S W G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25171 547 58832 S92 H N L V L T K S G D I Y S F G
Honey Bee Apis mellifera XP_394158 439 46956 T101 H N V C L R Q T G E V L T F G
Nematode Worm Caenorhab. elegans Q18211 569 61466 E203 H S A V L T S E G E V Y M C G
Sea Urchin Strong. purpuratus XP_001191815 424 45249 D90 H T V C I A Q D G A V Y T F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21827 482 52995 E102 H T L A L D E E S N V W S W G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 64.7 N.A. 93.8 93.3 N.A. N.A. 37 75.9 22.2 N.A. 29 45.5 29.5 52.8
Protein Similarity: 100 99.7 N.A. 65.8 N.A. 96.9 96.6 N.A. N.A. 42 85.6 40 N.A. 43.6 63 42.5 70.7
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 0 66.6 26.6 N.A. 60 53.3 40 60
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 80 80 N.A. 80 80 60 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 62 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 8 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 24 0 16 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % F
% Gly: 0 0 0 0 0 8 0 0 85 0 0 0 0 0 93 % G
% His: 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 16 0 0 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 31 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 24 0 77 0 0 0 0 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 16 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 31 0 0 39 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 16 0 0 0 39 8 54 8 8 0 0 62 0 0 % S
% Thr: 0 62 0 0 0 24 8 8 0 0 0 0 24 0 0 % T
% Val: 0 0 62 16 0 0 0 0 0 0 70 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 16 0 16 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _