KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2C
All Species:
17.88
Human Site:
S288
Identified Species:
39.33
UniProt:
P18825
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18825
NP_000674.2
462
49522
S288
A
D
V
E
P
D
E
S
S
A
A
A
E
R
R
Chimpanzee
Pan troglodytes
Q9N298
422
46153
A274
V
E
S
K
A
G
G
A
L
C
A
N
G
A
V
Rhesus Macaque
Macaca mulatta
XP_001114432
408
42792
H273
A
G
A
G
E
N
G
H
C
A
P
P
R
A
D
Dog
Lupus familis
XP_545911
714
73976
S296
A
D
V
D
P
E
D
S
S
A
A
A
E
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q01337
458
49888
S286
T
E
V
E
P
D
E
S
S
A
A
E
R
R
R
Rat
Rattus norvegicus
P22086
458
49846
S286
T
E
V
E
P
D
E
S
S
A
A
E
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519776
218
24278
A90
V
T
V
W
L
I
S
A
F
I
S
F
P
P
L
Chicken
Gallus gallus
XP_426355
614
69002
S460
E
D
I
E
L
E
E
S
S
T
S
E
S
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
S281
P
D
A
D
L
E
D
S
S
S
S
D
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22270
601
64656
E363
P
M
I
Q
N
D
Q
E
S
I
S
S
E
T
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
A291
A
D
P
D
I
Q
M
A
T
L
Q
V
D
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.9
80.3
59.6
N.A.
92.8
93
N.A.
35.9
53.7
N.A.
58.4
N.A.
32.7
N.A.
N.A.
33.3
Protein Similarity:
100
50
80.9
61.6
N.A.
93.5
93.7
N.A.
39.1
60.2
N.A.
70.1
N.A.
47.5
N.A.
N.A.
52.2
P-Site Identity:
100
6.6
13.3
80
N.A.
73.3
73.3
N.A.
6.6
46.6
N.A.
26.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
20
100
N.A.
80
80
N.A.
20
66.6
N.A.
66.6
N.A.
53.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
19
0
10
0
0
28
0
46
46
19
0
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
46
0
28
0
37
19
0
0
0
0
10
10
0
10
% D
% Glu:
10
28
0
37
10
28
37
10
0
0
0
28
37
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
10
0
10
0
10
19
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% H
% Ile:
0
0
19
0
10
10
0
0
0
19
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
28
0
0
0
10
10
0
0
0
0
10
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
19
0
10
0
37
0
0
0
0
0
10
10
10
10
0
% P
% Gln:
0
0
0
10
0
10
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
28
46
46
% R
% Ser:
0
0
10
0
0
0
10
55
64
10
37
10
10
0
0
% S
% Thr:
19
10
0
0
0
0
0
0
10
10
0
0
0
10
0
% T
% Val:
19
0
46
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _