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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2C
All Species:
17.27
Human Site:
S346
Identified Species:
38
UniProt:
P18825
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18825
NP_000674.2
462
49522
S346
P
G
P
G
G
R
L
S
R
A
S
S
R
S
V
Chimpanzee
Pan troglodytes
Q9N298
422
46153
S309
K
E
H
L
P
L
P
S
E
A
G
P
T
P
C
Rhesus Macaque
Macaca mulatta
XP_001114432
408
42792
R305
A
L
R
R
G
R
R
R
R
A
G
A
E
G
G
Dog
Lupus familis
XP_545911
714
73976
S363
P
G
P
G
G
R
L
S
R
A
S
S
R
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q01337
458
49888
S342
P
G
P
G
G
R
L
S
R
A
S
S
R
S
V
Rat
Rattus norvegicus
P22086
458
49846
S342
P
G
P
G
G
R
L
S
R
A
S
S
R
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519776
218
24278
L122
N
D
D
T
W
Y
I
L
A
S
C
V
G
S
F
Chicken
Gallus gallus
XP_426355
614
69002
S498
K
H
S
S
S
R
L
S
R
S
S
N
R
S
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
K318
S
S
K
H
S
S
R
K
S
R
A
S
S
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22270
601
64656
G493
T
P
P
Q
S
S
T
G
V
A
A
V
S
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
L356
M
R
A
S
D
T
H
L
R
P
D
T
P
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.9
80.3
59.6
N.A.
92.8
93
N.A.
35.9
53.7
N.A.
58.4
N.A.
32.7
N.A.
N.A.
33.3
Protein Similarity:
100
50
80.9
61.6
N.A.
93.5
93.7
N.A.
39.1
60.2
N.A.
70.1
N.A.
47.5
N.A.
N.A.
52.2
P-Site Identity:
100
13.3
26.6
100
N.A.
100
100
N.A.
6.6
46.6
N.A.
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
33.3
100
N.A.
100
100
N.A.
20
66.6
N.A.
13.3
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
10
64
19
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
10
10
0
10
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
37
0
37
46
0
0
10
0
0
19
0
10
10
10
% G
% His:
0
10
10
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
10
0
10
0
10
46
19
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
37
10
46
0
10
0
10
0
0
10
0
10
10
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
10
10
0
55
19
10
64
10
0
0
46
0
0
% R
% Ser:
10
10
10
19
28
19
0
55
10
19
46
46
19
55
10
% S
% Thr:
10
0
0
10
0
10
10
0
0
0
0
10
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
19
0
10
37
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _