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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2C
All Species:
20.3
Human Site:
S358
Identified Species:
44.67
UniProt:
P18825
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18825
NP_000674.2
462
49522
S358
R
S
V
E
F
F
L
S
R
R
R
R
A
R
S
Chimpanzee
Pan troglodytes
Q9N298
422
46153
F321
T
P
C
A
P
A
S
F
E
R
K
N
E
R
N
Rhesus Macaque
Macaca mulatta
XP_001114432
408
42792
D317
E
G
G
A
G
G
A
D
G
Q
G
A
A
E
S
Dog
Lupus familis
XP_545911
714
73976
S375
R
S
V
E
F
F
L
S
R
R
R
R
A
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q01337
458
49888
S354
R
S
V
E
F
F
L
S
R
R
R
R
A
R
S
Rat
Rattus norvegicus
P22086
458
49846
S354
R
S
V
E
F
F
L
S
R
R
R
R
A
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519776
218
24278
L134
G
S
F
F
A
P
C
L
I
M
I
L
V
Y
V
Chicken
Gallus gallus
XP_426355
614
69002
Y510
R
S
M
E
F
F
S
Y
R
R
R
R
K
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
S330
S
K
S
L
D
L
F
S
S
R
R
K
R
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22270
601
64656
K505
S
V
T
P
L
Q
K
K
T
S
G
V
N
Q
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
S368
P
Q
M
Q
H
R
P
S
R
I
D
P
H
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.9
80.3
59.6
N.A.
92.8
93
N.A.
35.9
53.7
N.A.
58.4
N.A.
32.7
N.A.
N.A.
33.3
Protein Similarity:
100
50
80.9
61.6
N.A.
93.5
93.7
N.A.
39.1
60.2
N.A.
70.1
N.A.
47.5
N.A.
N.A.
52.2
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
6.6
73.3
N.A.
26.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
20
100
N.A.
100
100
N.A.
6.6
80
N.A.
40
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
10
10
10
0
0
0
0
10
46
0
0
% A
% Cys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
46
0
0
0
0
10
0
0
0
10
19
0
% E
% Phe:
0
0
10
10
46
46
10
10
0
0
0
0
0
0
10
% F
% Gly:
10
10
10
0
10
10
0
0
10
0
19
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
10
% I
% Lys:
0
10
0
0
0
0
10
10
0
0
10
10
10
0
0
% K
% Leu:
0
0
0
10
10
10
37
10
0
0
0
10
0
0
0
% L
% Met:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
19
% N
% Pro:
10
10
0
10
10
10
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
10
0
10
0
10
0
0
0
10
0
0
0
10
0
% Q
% Arg:
46
0
0
0
0
10
0
0
55
64
55
46
10
64
0
% R
% Ser:
19
55
10
0
0
0
19
55
10
10
0
0
0
0
55
% S
% Thr:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
10
37
0
0
0
0
0
0
0
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _