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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2C
All Species:
18.48
Human Site:
S365
Identified Species:
40.67
UniProt:
P18825
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18825
NP_000674.2
462
49522
S365
S
R
R
R
R
A
R
S
S
V
C
R
R
K
V
Chimpanzee
Pan troglodytes
Q9N298
422
46153
N328
F
E
R
K
N
E
R
N
A
E
A
K
R
K
M
Rhesus Macaque
Macaca mulatta
XP_001114432
408
42792
S324
D
G
Q
G
A
A
E
S
G
A
L
T
A
S
R
Dog
Lupus familis
XP_545911
714
73976
S382
S
R
R
R
R
A
R
S
S
V
C
R
R
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q01337
458
49888
S361
S
R
R
R
R
A
R
S
S
V
C
R
R
K
V
Rat
Rattus norvegicus
P22086
458
49846
S361
S
R
R
R
R
A
R
S
S
V
C
R
R
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519776
218
24278
V141
L
I
M
I
L
V
Y
V
R
I
Y
Q
I
A
K
Chicken
Gallus gallus
XP_426355
614
69002
S517
Y
R
R
R
R
K
R
S
S
I
C
R
K
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
N337
S
S
R
R
K
R
R
N
T
I
S
R
K
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22270
601
64656
F512
K
T
S
G
V
N
Q
F
I
E
E
K
Q
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
I375
S
R
I
D
P
H
E
I
E
K
Q
K
R
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.9
80.3
59.6
N.A.
92.8
93
N.A.
35.9
53.7
N.A.
58.4
N.A.
32.7
N.A.
N.A.
33.3
Protein Similarity:
100
50
80.9
61.6
N.A.
93.5
93.7
N.A.
39.1
60.2
N.A.
70.1
N.A.
47.5
N.A.
N.A.
52.2
P-Site Identity:
100
26.6
13.3
100
N.A.
100
100
N.A.
0
73.3
N.A.
40
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
60
20
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
80
N.A.
33.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
46
0
0
10
10
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
19
0
10
19
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
19
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
10
0
0
0
10
10
28
0
0
10
0
19
% I
% Lys:
10
0
0
10
10
10
0
0
0
10
0
28
19
73
10
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
10
0
19
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
10
10
10
0
0
% Q
% Arg:
0
55
64
55
46
10
64
0
10
0
0
55
55
10
10
% R
% Ser:
55
10
10
0
0
0
0
55
46
0
10
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
10
0
10
0
37
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _