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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATF6 All Species: 11.82
Human Site: S141 Identified Species: 26
UniProt: P18850 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18850 NP_031374.2 670 74585 S141 L Y G E N S N S L S S A E P L
Chimpanzee Pan troglodytes XP_001174215 670 74514 S141 L Y G E N S N S P S S A E P L
Rhesus Macaque Macaca mulatta XP_001118153 620 68904 V105 P L K E D K P V T G P R N K T
Dog Lupus familis XP_545777 724 79935 H196 S L Y G E S S H S P S L A E P
Cat Felis silvestris
Mouse Mus musculus O35451 699 75989 S139 L L G D D P A S P F E T V Q I
Rat Rattus norvegicus Q5UEM7 367 40262
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520663 696 75605 S156 S P S S S S S S S S E S L A D
Chicken Gallus gallus XP_422208 634 70203 S119 I V G V T S R S A N N S V K T
Frog Xenopus laevis NP_001088791 525 57534 L10 A T V E S C V L G G L Q G P G
Zebra Danio Brachydanio rerio Q502F0 428 48228
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793757 622 68742 S107 S S D S S S E S S Q A S Q N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 90.9 84.3 N.A. 33.6 21.4 N.A. 61.4 59.5 42 20.2 N.A. N.A. N.A. N.A. 23.1
Protein Similarity: 100 99.6 91.7 88.1 N.A. 50.9 35 N.A. 72.1 72.6 56.5 34.7 N.A. N.A. N.A. N.A. 43.8
P-Site Identity: 100 93.3 6.6 13.3 N.A. 20 0 N.A. 20 20 13.3 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 13.3 20 N.A. 40 0 N.A. 40 46.6 20 0 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 10 0 10 19 10 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 19 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 37 10 0 10 0 0 0 19 0 19 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 37 10 0 0 0 0 10 19 0 0 10 0 19 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 10 0 0 10 0 0 0 0 0 0 0 19 0 % K
% Leu: 28 28 0 0 0 0 0 10 10 0 10 10 10 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 19 0 0 10 10 0 10 10 0 % N
% Pro: 10 10 0 0 0 10 10 0 19 10 10 0 0 28 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 10 10 10 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % R
% Ser: 28 10 10 19 28 55 19 55 28 28 28 28 0 0 0 % S
% Thr: 0 10 0 0 10 0 0 0 10 0 0 10 0 0 19 % T
% Val: 0 10 10 10 0 0 10 10 0 0 0 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _