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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG1
All Species:
26.36
Human Site:
S603
Identified Species:
52.73
UniProt:
P18858
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18858
NP_000225.1
919
101736
S603
G
K
Y
P
D
I
I
S
R
I
P
K
I
K
L
Chimpanzee
Pan troglodytes
XP_524321
919
101662
S603
G
K
Y
P
D
I
I
S
R
I
P
K
I
K
L
Rhesus Macaque
Macaca mulatta
XP_001111346
919
101454
S603
G
K
Y
P
D
I
I
S
R
I
P
K
I
K
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P37913
916
102271
S601
G
K
Y
P
D
I
I
S
R
I
P
K
I
K
H
Rat
Rattus norvegicus
Q9JHY8
918
102463
S603
G
K
Y
P
D
I
I
S
R
I
P
K
I
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P51892
1070
120215
S756
T
K
Y
P
D
I
I
S
R
I
P
K
I
K
K
Zebra Danio
Brachydanio rerio
NP_001119860
1058
118776
S745
S
K
Y
P
D
I
I
S
R
I
P
Q
V
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1H4
747
84700
K441
A
L
L
K
G
D
V
K
S
Y
I
I
D
S
E
Honey Bee
Apis mellifera
XP_392286
861
97795
G547
S
K
Y
P
D
I
I
G
R
F
K
N
T
Q
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180844
967
108403
A651
S
K
Y
P
D
I
I
A
R
L
S
S
S
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42572
790
87722
L484
V
A
L
A
L
S
R
L
K
K
P
S
V
K
S
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
Y449
G
E
N
M
T
E
R
Y
P
E
I
N
I
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.2
N.A.
N.A.
84
81.3
N.A.
N.A.
N.A.
56.9
56.1
N.A.
44
46
N.A.
48.5
Protein Similarity:
100
99.4
98.8
N.A.
N.A.
89.3
87.8
N.A.
N.A.
N.A.
71.1
68.6
N.A.
60.2
65.7
N.A.
66.2
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
73.3
N.A.
0
46.6
N.A.
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
86.6
N.A.
6.6
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.3
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.3
53.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
75
9
0
0
0
0
0
0
9
0
17
% D
% Glu:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
50
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
75
75
0
0
59
17
9
59
0
0
% I
% Lys:
0
75
0
9
0
0
0
9
9
9
9
50
0
67
17
% K
% Leu:
0
9
17
0
9
0
0
9
0
9
0
0
0
0
25
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
75
0
0
0
0
9
0
67
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
17
0
75
0
0
0
0
0
0
% R
% Ser:
25
0
0
0
0
9
0
59
9
0
9
17
9
9
9
% S
% Thr:
9
0
0
0
9
0
0
0
0
0
0
0
9
9
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
75
0
0
0
0
9
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _