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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG1
All Species:
19.39
Human Site:
T197
Identified Species:
38.79
UniProt:
P18858
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18858
NP_000225.1
919
101736
T197
T
S
K
A
E
T
P
T
E
S
V
S
E
P
E
Chimpanzee
Pan troglodytes
XP_524321
919
101662
T197
T
S
K
A
E
T
P
T
E
S
V
S
E
P
E
Rhesus Macaque
Macaca mulatta
XP_001111346
919
101454
T197
T
S
K
A
E
T
L
T
E
S
V
S
E
P
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P37913
916
102271
T195
S
P
E
S
V
T
L
T
K
T
E
N
I
P
V
Rat
Rattus norvegicus
Q9JHY8
918
102463
T197
S
P
E
S
V
T
L
T
K
T
E
N
I
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P51892
1070
120215
F330
K
F
S
D
K
V
S
F
K
D
N
D
S
E
E
Zebra Danio
Brachydanio rerio
NP_001119860
1058
118776
I325
G
E
N
E
K
E
K
I
P
D
K
K
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1H4
747
84700
L91
K
K
V
T
T
I
G
L
N
S
T
A
A
T
K
Honey Bee
Apis mellifera
XP_392286
861
97795
S190
E
S
S
S
E
I
E
S
S
K
S
S
S
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180844
967
108403
S226
K
S
R
K
D
K
S
S
P
S
D
K
K
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42572
790
87722
G134
I
A
E
D
S
K
T
G
A
K
K
A
K
T
L
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
S99
H
T
V
A
A
P
S
S
M
G
S
N
F
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.2
N.A.
N.A.
84
81.3
N.A.
N.A.
N.A.
56.9
56.1
N.A.
44
46
N.A.
48.5
Protein Similarity:
100
99.4
98.8
N.A.
N.A.
89.3
87.8
N.A.
N.A.
N.A.
71.1
68.6
N.A.
60.2
65.7
N.A.
66.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
93.3
N.A.
N.A.
60
60
N.A.
N.A.
N.A.
20
13.3
N.A.
20
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.3
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.3
53.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
34
9
0
0
0
9
0
0
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
9
0
0
0
0
17
9
9
0
0
0
% D
% Glu:
9
9
25
9
34
9
9
0
25
0
17
0
25
17
42
% E
% Phe:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
0
0
9
9
0
9
0
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
17
0
9
0
0
0
0
17
0
0
% I
% Lys:
25
9
25
9
17
17
9
0
25
17
17
17
17
9
25
% K
% Leu:
0
0
0
0
0
0
25
9
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
9
25
0
0
0
% N
% Pro:
0
17
0
0
0
9
17
0
17
0
0
0
0
42
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
42
17
25
9
0
25
25
9
42
17
34
17
17
9
% S
% Thr:
25
9
0
9
9
42
9
42
0
17
9
0
0
17
0
% T
% Val:
0
0
17
0
17
9
0
0
0
0
25
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _