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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 28.48
Human Site: S13 Identified Species: 62.67
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 S13 L R H V V S C S S Q D S T H C
Chimpanzee Pan troglodytes XP_512717 596 65689 S13 L R H V V S C S S Q D S T H C
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 Q34 V G T L Q C R Q K R R D W A C
Dog Lupus familis XP_533653 654 71801 S38 L R H V V S C S S Q D S T H C
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 S13 L R H V V S C S S Q D S T H C
Rat Rattus norvegicus Q9ESZ0 631 68817 S13 L R H V V S C S S Q D S T H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 S13 L K H V V S C S S A D T T H T
Zebra Danio Brachydanio rerio NP_001003988 615 68071 S13 L K H V V S C S S E D N T H K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 S13 F K S V R E V S S E D A V H V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 100 6.6 100 N.A. 100 93.3 N.A. 0 N.A. 73.3 73.3 N.A. 33.3 N.A. N.A. 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 93.3 N.A. 0 N.A. 86.6 93.3 N.A. 53.3 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 10 64 0 0 0 0 0 0 0 46 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 73 10 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 19 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 64 0 0 0 0 0 0 0 0 0 0 73 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 28 0 0 0 0 0 0 10 0 0 0 0 0 10 % K
% Leu: 64 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 10 0 46 0 0 0 0 0 % Q
% Arg: 0 46 0 0 10 0 10 0 0 10 10 0 0 0 10 % R
% Ser: 0 0 10 0 0 64 0 73 73 0 0 46 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 10 64 0 10 % T
% Val: 10 0 0 73 64 0 10 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _