Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 16.97
Human Site: S137 Identified Species: 37.33
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 S137 I V C S Q P Y S K D S P F G L
Chimpanzee Pan troglodytes XP_512717 596 65689 E122 P P D K D E A E A P S Q K V T
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 V169 S A F V E V L V G S S A G G A
Dog Lupus familis XP_533653 654 71801 P160 V K I V C S Q P Y S K D S P Y
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 S139 I V C S Q P Y S K D S P Y G L
Rat Rattus norvegicus Q9ESZ0 631 68817 S139 I V C S Q P Y S K D S P Y G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237 T99 G P D K L V R T V A E K R W D
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 T136 I V C T Q P Y T K N L A Y G L
Zebra Danio Brachydanio rerio NP_001003988 615 68071 S136 I V C S Q P Y S K T I A Y G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 N135 I V C T Q P F N R H V P Y G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847 I61 Q L D K A S N I H S I D V G N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 6.6 13.3 0 N.A. 93.3 93.3 N.A. 0 N.A. 60 66.6 N.A. 53.3 N.A. N.A. 6.6
P-Site Similarity: 100 6.6 20 6.6 N.A. 100 100 N.A. 6.6 N.A. 86.6 80 N.A. 86.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 10 0 10 10 0 28 0 0 10 % A
% Cys: 0 0 55 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 28 0 10 0 0 0 0 28 0 19 0 0 10 % D
% Glu: 0 0 0 0 10 10 0 10 0 0 10 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 10 0 0 0 0 0 10 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 0 0 0 10 73 0 % G
% His: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % H
% Ile: 55 0 10 0 0 0 0 10 0 0 19 0 0 0 10 % I
% Lys: 0 10 0 28 0 0 0 0 46 0 10 10 10 0 0 % K
% Leu: 0 10 0 0 10 0 10 0 0 0 10 0 0 0 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 10 % N
% Pro: 10 19 0 0 0 55 0 10 0 10 0 37 0 10 0 % P
% Gln: 10 0 0 0 55 0 10 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 0 0 0 10 0 0 % R
% Ser: 10 0 0 37 0 19 0 37 0 28 46 0 10 0 0 % S
% Thr: 0 0 0 19 0 0 0 19 0 10 0 0 0 0 10 % T
% Val: 10 55 0 19 0 19 0 10 10 0 10 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 46 0 10 0 0 0 46 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _