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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
13.03
Human Site:
S224
Identified Species:
28.67
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S224
Q
A
S
S
A
A
S
S
A
S
P
V
S
R
A
Chimpanzee
Pan troglodytes
XP_512717
596
65689
R209
Q
E
S
P
K
G
K
R
K
L
D
L
N
Q
E
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
E256
P
P
D
K
D
E
A
E
A
P
S
Q
K
V
T
Dog
Lupus familis
XP_533653
654
71801
S247
Q
A
S
S
A
T
S
S
P
S
A
A
S
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
S226
Q
A
S
S
A
A
S
S
A
S
P
V
P
K
V
Rat
Rattus norvegicus
Q9ESZ0
631
68817
S226
Q
A
S
S
A
A
S
S
A
S
P
V
P
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
G186
G
P
A
G
G
Q
P
G
P
S
Y
A
A
A
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
S223
G
T
A
E
S
S
S
S
T
E
K
Q
T
V
K
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
G223
A
A
A
L
K
T
E
G
S
S
T
H
T
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
R222
A
G
S
T
A
L
R
R
L
S
A
G
K
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
Q148
A
S
S
I
P
P
S
Q
Q
A
S
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
13.3
6.6
73.3
N.A.
80
80
N.A.
6.6
N.A.
13.3
20
N.A.
20
N.A.
N.A.
20
P-Site Similarity:
100
33.3
13.3
73.3
N.A.
86.6
86.6
N.A.
20
N.A.
40
40
N.A.
33.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
46
28
0
46
28
10
0
37
10
19
19
10
10
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
10
0
10
10
10
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
0
10
10
10
0
19
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
19
0
10
0
10
0
10
0
19
19
10
% K
% Leu:
0
0
0
10
0
10
0
0
10
10
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
19
0
10
10
10
10
0
19
10
28
0
19
10
0
% P
% Gln:
46
0
0
0
0
10
0
10
10
0
0
19
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
19
0
0
0
0
0
19
0
% R
% Ser:
0
10
64
37
10
10
55
46
10
64
19
10
28
10
19
% S
% Thr:
0
10
0
10
0
19
0
0
10
0
10
0
19
0
19
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
28
0
28
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _