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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
14.85
Human Site:
S259
Identified Species:
32.67
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S259
Q
E
E
K
K
T
P
S
K
P
P
A
Q
L
S
Chimpanzee
Pan troglodytes
XP_512717
596
65689
R243
P
K
L
P
A
P
T
R
T
P
A
T
A
P
V
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
S301
K
T
S
P
V
T
A
S
D
P
A
G
P
S
Y
Dog
Lupus familis
XP_533653
654
71801
S282
Q
E
E
R
K
T
P
S
K
P
S
A
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
S261
L
E
D
R
K
P
P
S
K
P
S
A
G
P
S
Rat
Rattus norvegicus
Q9ESZ0
631
68817
S261
L
E
D
K
K
P
P
S
K
P
S
A
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
S220
P
P
S
S
S
S
S
S
S
S
N
K
V
R
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
S268
K
K
P
E
V
K
E
S
P
S
S
T
K
E
S
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
K258
A
S
G
P
P
A
K
K
P
S
S
S
A
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
A258
V
S
P
T
P
L
D
A
K
P
L
D
R
N
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
S182
D
K
K
E
G
E
N
S
H
K
R
P
A
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
6.6
20
80
N.A.
53.3
53.3
N.A.
6.6
N.A.
13.3
0
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
26.6
86.6
N.A.
66.6
60
N.A.
13.3
N.A.
40
13.3
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
10
10
10
0
0
19
37
28
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
0
0
0
10
0
10
0
0
10
0
0
0
% D
% Glu:
0
37
19
19
0
10
10
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
0
0
0
10
19
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
28
10
19
37
10
10
10
46
10
0
10
10
0
0
% K
% Leu:
19
0
10
0
0
10
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% N
% Pro:
19
10
19
28
19
28
37
0
19
64
10
10
10
37
10
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% Q
% Arg:
0
0
0
19
0
0
0
10
0
0
10
0
10
10
10
% R
% Ser:
0
19
19
10
10
10
10
73
10
28
46
10
0
19
37
% S
% Thr:
0
10
0
10
0
28
10
0
10
0
0
19
0
0
0
% T
% Val:
10
0
0
0
19
0
0
0
0
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _