KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
5.15
Human Site:
S268
Identified Species:
11.33
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S268
P
P
A
Q
L
S
P
S
V
P
K
R
P
K
L
Chimpanzee
Pan troglodytes
XP_512717
596
65689
A252
P
A
T
A
P
V
P
A
R
A
Q
G
A
V
T
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
A310
P
A
G
P
S
Y
A
A
A
T
L
Q
A
S
S
Dog
Lupus familis
XP_533653
654
71801
P291
P
S
A
Q
P
S
P
P
A
I
K
R
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
L270
P
S
A
G
P
S
T
L
K
R
P
K
L
S
V
Rat
Rattus norvegicus
Q9ESZ0
631
68817
P270
P
S
A
G
P
P
A
P
K
R
P
K
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
S229
S
N
K
V
R
G
A
S
P
T
E
A
P
G
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
S277
S
S
T
K
E
S
L
S
Q
P
V
P
K
K
P
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
T267
S
S
S
A
S
A
E
T
T
P
K
A
K
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
S267
P
L
D
R
N
R
A
S
L
L
F
G
D
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
K191
K
R
P
A
V
E
P
K
R
E
E
P
R
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
13.3
6.6
60
N.A.
20
13.3
N.A.
13.3
N.A.
26.6
13.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
20
60
N.A.
33.3
26.6
N.A.
20
N.A.
33.3
33.3
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
37
28
0
10
37
19
19
10
0
19
19
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
10
% D
% Glu:
0
0
0
0
10
10
10
0
0
10
19
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
19
0
10
0
0
0
0
0
19
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
10
10
0
0
0
10
19
0
28
19
19
28
10
% K
% Leu:
0
10
0
0
10
0
10
10
10
10
10
0
19
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
64
10
10
10
37
10
37
19
10
28
19
19
28
10
19
% P
% Gln:
0
0
0
19
0
0
0
0
10
0
10
10
0
0
0
% Q
% Arg:
0
10
0
10
10
10
0
0
19
19
0
19
10
10
10
% R
% Ser:
28
46
10
0
19
37
0
37
0
0
0
0
0
19
10
% S
% Thr:
0
0
19
0
0
0
10
10
10
19
0
0
0
0
10
% T
% Val:
0
0
0
10
10
10
0
0
10
0
10
0
0
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _