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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
13.03
Human Site:
S398
Identified Species:
28.67
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S398
R
M
R
R
R
L
P
S
R
R
Y
L
M
A
G
Chimpanzee
Pan troglodytes
XP_512717
596
65689
S361
R
M
R
R
R
L
P
S
R
R
Y
L
M
A
G
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
Q428
V
V
V
L
S
G
F
Q
N
P
F
R
S
E
L
Dog
Lupus familis
XP_533653
654
71801
S419
R
M
R
R
R
L
P
S
R
R
Y
L
M
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
P397
H
H
M
R
R
R
L
P
S
R
R
Y
L
M
A
Rat
Rattus norvegicus
Q9ESZ0
631
68817
P397
Y
R
M
R
R
R
L
P
S
R
R
Y
L
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
S338
Y
L
M
A
G
P
R
S
S
S
E
E
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
Y399
K
K
R
Q
R
L
P
Y
K
Q
Y
L
L
G
A
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
V388
I
I
V
R
K
E
W
V
M
D
C
H
K
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
D379
K
H
D
H
R
S
S
D
T
S
N
S
K
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
I300
K
R
T
L
L
P
W
I
R
Y
K
L
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
100
0
100
N.A.
20
20
N.A.
6.6
N.A.
40
6.6
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
13.3
100
N.A.
26.6
26.6
N.A.
13.3
N.A.
73.3
20
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
28
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
10
10
10
28
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
0
0
0
10
37
% G
% His:
10
19
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
28
10
0
0
10
0
0
0
10
0
10
0
19
0
10
% K
% Leu:
0
10
0
19
10
37
19
0
0
0
0
46
28
0
10
% L
% Met:
0
28
28
0
0
0
0
0
10
0
0
0
28
19
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
19
37
19
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
28
19
37
55
64
19
10
0
37
46
19
10
0
0
0
% R
% Ser:
0
0
0
0
10
10
10
37
28
19
0
10
19
10
10
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
10
10
19
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
0
0
10
0
10
37
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _