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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
16.06
Human Site:
S446
Identified Species:
35.33
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S446
P
T
Q
A
A
G
P
S
S
P
Q
K
P
P
T
Chimpanzee
Pan troglodytes
XP_512717
596
65689
S409
P
T
Q
A
A
G
P
S
S
P
Q
K
P
P
T
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
R476
Q
V
L
G
L
G
G
R
I
V
R
K
E
W
V
Dog
Lupus familis
XP_533653
654
71801
S467
L
P
Q
A
A
G
P
S
S
P
Q
R
P
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
S445
K
T
Q
A
A
G
P
S
S
P
P
R
P
P
T
Rat
Rattus norvegicus
Q9ESZ0
631
68817
S445
K
T
Q
A
A
G
P
S
S
P
P
R
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
G386
A
R
A
G
S
P
P
G
P
Q
T
P
E
E
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
A447
K
K
P
L
P
S
P
A
K
A
K
E
K
R
A
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
V436
K
T
P
E
K
K
P
V
T
P
K
K
Q
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
G427
P
L
N
Q
L
L
K
G
V
V
L
V
I
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
K348
Q
P
K
T
P
T
P
K
K
P
A
D
V
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
100
13.3
73.3
N.A.
80
80
N.A.
13.3
N.A.
6.6
26.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
20
80
N.A.
86.6
86.6
N.A.
20
N.A.
26.6
40
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
46
46
0
0
10
0
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
10
19
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
19
0
55
10
19
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
37
10
10
0
10
10
10
10
19
0
19
37
10
10
0
% K
% Leu:
10
10
10
10
19
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
28
19
19
0
19
10
82
0
10
64
19
10
46
37
10
% P
% Gln:
19
0
46
10
0
0
0
0
0
10
28
0
10
10
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
10
28
0
10
0
% R
% Ser:
0
0
0
0
10
10
0
46
46
0
0
0
0
10
0
% S
% Thr:
0
46
0
10
0
10
0
0
10
0
10
0
0
0
55
% T
% Val:
0
10
0
0
0
0
0
10
10
19
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _