KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
26.36
Human Site:
S518
Identified Species:
58
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S518
G
E
D
P
Y
A
G
S
T
D
E
N
T
D
S
Chimpanzee
Pan troglodytes
XP_512717
596
65689
S481
G
E
D
P
Y
A
G
S
T
D
E
N
T
D
S
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
T537
P
Q
T
K
T
K
P
T
Q
A
T
G
P
S
L
Dog
Lupus familis
XP_533653
654
71801
S539
G
E
D
P
Y
A
G
S
T
D
E
N
T
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
S517
G
E
D
P
Y
A
G
S
T
D
E
N
T
D
S
Rat
Rattus norvegicus
Q9ESZ0
631
68817
S517
G
E
D
P
Y
A
G
S
T
D
E
N
T
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
N446
R
P
P
E
E
V
K
N
G
E
D
P
Y
G
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
S537
P
E
D
P
Y
A
G
S
T
D
E
N
T
D
V
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
S505
N
E
D
P
Y
G
G
S
T
D
E
N
T
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
W489
G
K
I
V
T
R
S
W
I
E
K
C
Y
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
Q408
G
S
P
C
K
K
G
Q
S
S
S
P
G
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
0
N.A.
86.6
80
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
20
N.A.
86.6
86.6
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
55
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
64
0
0
0
0
0
0
64
10
0
0
64
0
% D
% Glu:
0
64
0
10
10
0
0
0
0
19
64
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
64
0
0
0
0
10
73
0
10
0
0
10
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
10
0
10
10
19
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
64
0
0
0
% N
% Pro:
19
10
19
64
0
0
10
0
0
0
0
19
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
10
64
10
10
10
0
0
10
37
% S
% Thr:
0
0
10
0
19
0
0
10
64
0
10
0
64
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
64
0
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _