Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 2.12
Human Site: T296 Identified Species: 4.67
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 T296 A R A Q G A V T G K P R G E G
Chimpanzee Pan troglodytes XP_512717 596 65689 G280 R A G P E E L G K I L Q G V V
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 S338 S T S K P Q E S P K G K R K L
Dog Lupus familis XP_533653 654 71801 G319 P A R G T V P G K T R E G A E
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 K298 A Q R A V P G K P R G E G T E
Rat Rattus norvegicus Q9ESZ0 631 68817 K298 A Q K A V P G K P R G E G T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237 R257 S G K K L G G R G P G K N A G
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 Q305 S P S E K P T Q K K S P S A P
Zebra Danio Brachydanio rerio NP_001003988 615 68071 R295 A Q K S S D K R E S P K T K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 A295 R L S K H L E A D K D R R R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847 G219 P A T G E A F G K L M K K V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 6.6 6.6 6.6 N.A. 13.3 13.3 N.A. 13.3 N.A. 6.6 13.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 20 46.6 6.6 N.A. 26.6 26.6 N.A. 33.3 N.A. 26.6 33.3 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 28 10 19 0 19 0 10 0 0 0 0 0 28 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % D
% Glu: 0 0 0 10 19 10 19 0 10 0 0 28 0 10 28 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 19 10 10 28 28 19 0 37 0 46 0 19 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 28 28 10 0 10 19 37 37 0 37 10 19 0 % K
% Leu: 0 10 0 0 10 10 10 0 0 10 10 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 19 10 0 10 10 28 10 0 28 10 19 10 0 0 19 % P
% Gln: 0 28 0 10 0 10 0 10 0 0 0 10 0 0 0 % Q
% Arg: 19 10 19 0 0 0 0 19 0 19 10 19 19 10 0 % R
% Ser: 28 0 28 10 10 0 0 10 0 10 10 0 10 0 0 % S
% Thr: 0 10 10 0 10 0 10 10 0 10 0 0 10 19 0 % T
% Val: 0 0 0 0 19 10 10 0 0 0 0 0 0 19 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _