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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 21.52
Human Site: Y551 Identified Species: 47.33
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 Y551 Q G K H F F L Y G E F P G D E
Chimpanzee Pan troglodytes XP_512717 596 65689 Y514 Q G K H F F L Y G E F P G D E
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 V560 E T K A A S P V L Q E D I D I
Dog Lupus familis XP_533653 654 71801 Y572 Q G K H F F L Y G E F P G D E
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 Y549 E G K H F F L Y G E F P G D E
Rat Rattus norvegicus Q9ESZ0 631 68817 Y549 Q G K H F F L Y G E F P G D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237 D468 N E E T E T P D X Y Q S D S F
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 Y569 L G K K F F L Y G E F P A A E
Zebra Danio Brachydanio rerio NP_001003988 615 68071 K528 P E L P D F L K G K R F Y L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 Q514 L D T N D I G Q P E S D E E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847 F430 S S K R F F L F G K F D K E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 100 13.3 100 N.A. 93.3 100 N.A. 0 N.A. 73.3 20 N.A. 6.6 N.A. N.A. 46.6
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 6.6 N.A. 73.3 26.6 N.A. 20 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 19 0 0 10 0 0 0 28 10 55 0 % D
% Glu: 19 19 10 0 10 0 0 0 0 64 10 0 10 19 64 % E
% Phe: 0 0 0 0 64 73 0 10 0 0 64 10 0 0 10 % F
% Gly: 0 55 0 0 0 0 10 0 73 0 0 0 46 0 0 % G
% His: 0 0 0 46 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 73 10 0 0 0 10 0 19 0 0 10 0 0 % K
% Leu: 19 0 10 0 0 0 73 0 10 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 10 0 0 19 0 10 0 0 55 0 0 0 % P
% Gln: 37 0 0 0 0 0 0 10 0 10 10 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 10 0 0 0 10 0 0 0 0 10 10 0 10 0 % S
% Thr: 0 10 10 10 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 0 10 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _