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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT4 All Species: 2.73
Human Site: S64 Identified Species: 7.5
UniProt: P19013 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19013 NP_002263.2 534 57285 S64 G N K S I S M S V A G S R Q G
Chimpanzee Pan troglodytes A5A6M8 592 62520 S77 G S K W I S I S T S G G S F R
Rhesus Macaque Macaca mulatta XP_001099304 520 56069 G56 S R S L Y N L G G N K S I S M
Dog Lupus familis XP_543641 535 57544 F57 C G P G K G G F G S R S L Y N
Cat Felis silvestris
Mouse Mus musculus P07744 525 56265 K59 L Y N L G G H K S I S M S V A
Rat Rattus norvegicus Q6IG00 536 57648 K59 L Y N L G G H K S I S M S V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521385 725 77472 I65 S L G G T R S I S L N V A G G
Chicken Gallus gallus O93532 492 53785 A51 S L Y N L G S A N K R I S L G
Frog Xenopus laevis P16878 513 55433 V56 S L S N L G S V K R S V S Y G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.8 94.7 59.6 N.A. 81.4 78.3 N.A. 47.8 57.6 56.5 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.9 95.6 74.5 N.A. 88 87.3 N.A. 58.3 72.4 72 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 6.6 6.6 N.A. 0 0 N.A. 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 20 13.3 N.A. 0 0 N.A. 6.6 26.6 20 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 12 0 0 12 0 23 % A
% Cys: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 0 % F
% Gly: 23 12 12 23 23 56 12 12 23 0 23 12 0 12 45 % G
% His: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 23 0 12 12 0 23 0 12 12 0 0 % I
% Lys: 0 0 23 0 12 0 0 23 12 12 12 0 0 0 0 % K
% Leu: 23 34 0 34 23 0 12 0 0 12 0 0 12 12 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 23 0 0 12 % M
% Asn: 0 12 23 23 0 12 0 0 12 12 12 0 0 0 12 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Q
% Arg: 0 12 0 0 0 12 0 0 0 12 23 0 12 0 12 % R
% Ser: 45 12 23 12 0 23 34 23 34 23 34 34 56 12 0 % S
% Thr: 0 0 0 0 12 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 12 12 0 0 23 0 23 0 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 12 0 12 0 0 0 0 0 0 0 0 23 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _