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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDH2 All Species: 26.36
Human Site: S61 Identified Species: 64.44
UniProt: P19022 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19022 NP_001783.2 906 99809 S61 P L L N V K F S N C N G K R K
Chimpanzee Pan troglodytes XP_523898 1236 135068 S392 P L L N V K F S N C N G K R K
Rhesus Macaque Macaca mulatta XP_001100341 916 101235 S71 P L L N V K F S N C N G K R K
Dog Lupus familis XP_537293 1074 118057 S229 P L L N V K F S N C N G K R K
Cat Felis silvestris
Mouse Mus musculus P15116 906 99743 S61 P L L N V K F S N C N R K R K
Rat Rattus norvegicus Q9Z1Y3 906 99668 S61 P L L N V K F S N C N R K R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515514 902 99677 A63 G D R R V Q Y A S S E P A D F
Chicken Gallus gallus P10288 912 100446 Q66 P L L N V R F Q S C D E N R K
Frog Xenopus laevis P33147 906 100375 T64 P L L N V K F T D C G A D R R
Zebra Danio Brachydanio rerio Q90275 893 98972 S68 G S G L R F E S G D P A D F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73 96.6 83.1 N.A. 96.2 96.2 N.A. 90.4 85.6 80.2 71.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.1 97.4 83.8 N.A. 97.6 97.9 N.A. 94.6 92.6 88.1 83.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 6.6 60 60 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 33.3 80 80 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 20 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 10 10 10 0 20 10 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 10 80 0 0 0 0 0 0 10 10 % F
% Gly: 20 0 10 0 0 0 0 0 10 0 10 40 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 70 0 0 0 0 0 0 60 0 70 % K
% Leu: 0 80 80 10 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 80 0 0 0 0 60 0 60 0 10 0 0 % N
% Pro: 80 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 10 10 10 0 0 0 0 0 20 0 80 20 % R
% Ser: 0 10 0 0 0 0 0 70 20 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _