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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN8
All Species:
7.88
Human Site:
S45
Identified Species:
19.26
UniProt:
P19075
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19075
NP_004607.1
237
26044
S45
D
S
Q
A
I
F
G
S
E
D
V
G
S
S
S
Chimpanzee
Pan troglodytes
XP_001157562
237
26093
S45
D
S
Q
A
I
F
G
S
E
D
V
G
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001117478
237
25761
S45
D
S
Q
G
I
L
N
S
T
D
V
G
S
S
S
Dog
Lupus familis
XP_531678
237
25784
P45
D
G
Q
E
I
L
S
P
G
D
S
G
T
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P40240
226
25239
Q47
Q
T
K
S
I
F
E
Q
E
N
N
H
S
S
F
Rat
Rattus norvegicus
P40241
226
25196
Q47
Q
T
K
S
I
F
E
Q
E
T
N
H
S
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416096
241
26906
I45
D
A
Q
E
A
L
N
I
N
N
S
N
M
F
V
Frog
Xenopus laevis
Q6DCQ3
239
26764
P46
G
N
F
A
T
F
S
P
S
F
P
S
L
S
A
Zebra Danio
Brachydanio rerio
Q6GMK6
239
26765
P46
G
S
F
A
T
F
S
P
S
F
P
S
L
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140831
236
25886
D51
L
L
Y
L
E
L
G
D
K
P
A
P
S
T
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
82.6
74.2
N.A.
36.7
36.7
N.A.
N.A.
55.5
36.4
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
90.7
84.3
N.A.
55.2
55.7
N.A.
N.A.
71.3
54.8
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
40
N.A.
33.3
33.3
N.A.
N.A.
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
46.6
N.A.
60
53.3
N.A.
N.A.
26.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
40
10
0
0
0
0
0
10
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
10
0
40
0
0
0
0
0
% D
% Glu:
0
0
0
20
10
0
20
0
40
0
0
0
0
0
0
% E
% Phe:
0
0
20
0
0
60
0
0
0
20
0
0
0
10
30
% F
% Gly:
20
10
0
10
0
0
30
0
10
0
0
40
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
0
0
0
60
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
10
0
10
0
40
0
0
0
0
0
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
20
0
10
20
20
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
30
0
10
20
10
0
0
10
% P
% Gln:
20
0
50
0
0
0
0
20
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
40
0
20
0
0
30
30
20
0
20
20
60
80
30
% S
% Thr:
0
20
0
0
20
0
0
0
10
10
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
30
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _