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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN8
All Species:
6.06
Human Site:
Y122
Identified Species:
14.81
UniProt:
P19075
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19075
NP_004607.1
237
26044
Y122
R
I
V
N
E
T
L
Y
E
N
T
K
L
L
S
Chimpanzee
Pan troglodytes
XP_001157562
237
26093
Y122
R
I
V
N
E
T
L
Y
E
N
T
K
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001117478
237
25761
H122
R
I
I
N
E
T
L
H
D
N
T
E
L
L
S
Dog
Lupus familis
XP_531678
237
25784
H122
R
I
L
N
E
T
L
H
E
N
I
K
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P40240
226
25239
K124
K
E
L
Q
E
F
Y
K
D
T
Y
Q
K
L
R
Rat
Rattus norvegicus
P40241
226
25196
K124
K
E
L
Q
E
F
Y
K
D
T
Y
Q
K
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416096
241
26906
T120
E
G
F
N
L
V
I
T
E
A
A
N
L
L
K
Frog
Xenopus laevis
Q6DCQ3
239
26764
K120
E
N
A
K
Q
D
L
K
D
G
L
L
L
Y
N
Zebra Danio
Brachydanio rerio
Q6GMK6
239
26765
K120
E
N
A
K
Q
D
L
K
D
G
L
R
L
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140831
236
25886
D128
K
D
V
K
Q
F
Y
D
Q
A
L
Q
Q
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
82.6
74.2
N.A.
36.7
36.7
N.A.
N.A.
55.5
36.4
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
90.7
84.3
N.A.
55.2
55.7
N.A.
N.A.
71.3
54.8
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
80
N.A.
13.3
13.3
N.A.
N.A.
26.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
40
40
N.A.
N.A.
33.3
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
0
0
20
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
20
0
10
50
0
0
0
0
0
0
% D
% Glu:
30
20
0
0
60
0
0
0
40
0
0
10
0
0
0
% E
% Phe:
0
0
10
0
0
30
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
20
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
0
40
10
0
0
0
10
0
0
0
10
0
0
0
0
% I
% Lys:
30
0
0
30
0
0
0
40
0
0
0
30
20
0
10
% K
% Leu:
0
0
30
0
10
0
60
0
0
0
30
10
70
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
50
0
0
0
0
0
40
0
10
0
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
30
0
0
0
10
0
0
30
10
0
0
% Q
% Arg:
40
0
0
0
0
0
0
0
0
0
0
10
0
0
20
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% S
% Thr:
0
0
0
0
0
40
0
10
0
20
30
0
0
0
0
% T
% Val:
0
0
30
0
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
30
20
0
0
20
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _