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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCG1
All Species:
23.64
Human Site:
T932
Identified Species:
47.27
UniProt:
P19174
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19174
NP_002651.2
1290
148532
T932
K
I
R
E
V
A
Q
T
A
D
A
R
L
T
E
Chimpanzee
Pan troglodytes
XP_514650
1630
185027
T1272
K
I
R
E
V
A
Q
T
A
D
A
R
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001087295
1291
148567
T932
K
I
R
E
V
A
Q
T
A
D
A
R
L
T
E
Dog
Lupus familis
XP_542998
1249
143812
T892
K
I
R
E
V
A
Q
T
A
D
A
R
L
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62077
1302
149650
T932
K
I
R
E
V
A
Q
T
A
D
A
R
L
T
E
Rat
Rattus norvegicus
P10686
1290
148530
T932
K
I
R
E
V
A
Q
T
A
D
A
R
L
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
G305
L
V
K
N
K
K
C
G
T
I
E
E
T
M
L
Frog
Xenopus laevis
Q32NH8
758
87399
L426
R
L
P
S
P
D
E
L
R
G
K
I
L
L
K
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
R452
S
P
E
E
L
K
G
R
I
L
L
K
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
S763
R
F
G
V
Y
E
E
S
G
K
I
L
G
Q
R
Honey Bee
Apis mellifera
XP_624101
1134
132613
V802
G
A
V
V
E
L
R
V
G
G
R
P
D
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784329
940
107748
G608
F
S
E
E
R
I
P
G
K
Y
F
E
M
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79
99.5
93.2
N.A.
95.3
96.9
N.A.
N.A.
21.4
21.7
21.8
N.A.
21.4
45.1
N.A.
35.1
Protein Similarity:
100
79
99.7
94.5
N.A.
96.7
98.2
N.A.
N.A.
32.4
37.3
36.3
N.A.
40
62
N.A.
50
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
33.3
26.6
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
50
0
0
50
0
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
50
0
0
9
0
0
% D
% Glu:
0
0
17
67
9
9
17
0
0
0
9
17
0
0
50
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
9
0
0
0
9
17
17
17
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
9
0
0
9
9
9
9
0
0
0
% I
% Lys:
50
0
9
0
9
17
0
0
9
9
9
9
0
9
25
% K
% Leu:
9
9
0
0
9
9
0
9
0
9
9
9
59
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
9
0
9
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
0
0
0
0
9
0
% Q
% Arg:
17
0
50
0
9
0
9
9
9
0
9
50
0
0
9
% R
% Ser:
9
9
0
9
0
0
0
9
0
0
0
0
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
50
9
0
0
0
9
50
0
% T
% Val:
0
9
9
17
50
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _