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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UGT1A6 All Species: 13.03
Human Site: S41 Identified Species: 71.67
UniProt: P19224 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19224 NP_001063.2 532 60751 S41 Q D G S H W L S M K D I V E V
Chimpanzee Pan troglodytes XP_001151168 532 60662 S41 Q D G S H W L S M K D I V E V
Rhesus Macaque Macaca mulatta Q9GLD9 529 60840 N38 A E Y S H W M N M K T I L E E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64435 531 60420 S41 Q D G S H W L S M K E I V E H
Rat Rattus norvegicus P08430 529 60114 S40 Q D G S H W L S M K E I V E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 44.1 N.A. N.A. 79.5 79.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 62 N.A. N.A. 89.2 89.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 46.6 N.A. N.A. 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 80 0 0 0 0 0 0 0 0 40 0 0 0 0 % D
% Glu: 0 20 0 0 0 0 0 0 0 0 40 0 0 100 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 40 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 80 0 0 0 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 20 0 100 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 0 0 80 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 40 % V
% Trp: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _