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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI1
All Species:
12.12
Human Site:
T54
Identified Species:
29.63
UniProt:
P19237
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19237
NP_003272.3
187
21692
T54
E
R
I
P
T
L
Q
T
R
G
L
S
L
S
A
Chimpanzee
Pan troglodytes
XP_001146836
166
19254
D43
L
S
L
S
A
L
Q
D
L
C
R
E
L
H
A
Rhesus Macaque
Macaca mulatta
XP_001117040
182
21294
I54
E
H
C
P
P
L
H
I
P
G
S
M
S
E
V
Dog
Lupus familis
XP_851068
182
21393
L54
E
H
C
P
P
L
H
L
P
G
S
M
S
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ5
187
21680
T54
E
R
I
P
T
L
Q
T
R
G
L
S
L
S
A
Rat
Rattus norvegicus
P13413
187
21706
T54
E
R
I
P
T
L
Q
T
R
G
L
S
L
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P68246
183
21216
L54
E
H
C
P
P
L
S
L
P
G
S
M
Q
E
L
Frog
Xenopus laevis
P50754
244
28179
L110
E
H
C
Q
P
L
Q
L
S
G
L
S
R
S
E
Zebra Danio
Brachydanio rerio
NP_001008613
182
21013
T54
E
K
A
P
Q
L
Q
T
S
G
M
S
F
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GYF1
242
27542
D78
E
R
Q
K
A
L
A
D
R
T
I
S
L
P
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
57.7
56.6
N.A.
97.8
97.3
N.A.
N.A.
60.9
48.3
77.5
N.A.
N.A.
N.A.
24.7
N.A.
Protein Similarity:
100
88.7
74.8
75.4
N.A.
99.4
98.9
N.A.
N.A.
73.8
59.4
87.6
N.A.
N.A.
N.A.
42.5
N.A.
P-Site Identity:
100
26.6
26.6
26.6
N.A.
100
100
N.A.
N.A.
26.6
46.6
46.6
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
100
33.3
26.6
26.6
N.A.
100
100
N.A.
N.A.
26.6
46.6
66.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
20
0
10
0
0
0
0
0
0
10
40
% A
% Cys:
0
0
40
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% D
% Glu:
90
0
0
0
0
0
0
0
0
0
0
10
0
30
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% G
% His:
0
40
0
0
0
0
20
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
30
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
100
0
30
10
0
40
0
50
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
30
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
70
40
0
0
0
30
0
0
0
0
10
0
% P
% Gln:
0
0
10
10
10
0
60
0
0
0
0
0
10
0
0
% Q
% Arg:
0
40
0
0
0
0
0
0
40
0
10
0
10
0
0
% R
% Ser:
0
10
0
10
0
0
10
0
20
0
30
60
20
40
0
% S
% Thr:
0
0
0
0
30
0
0
40
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _