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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
26.06
Human Site:
S41
Identified Species:
57.33
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
S41
S
E
D
E
E
D
D
S
S
G
E
E
V
V
I
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
S312
S
E
D
E
E
D
D
S
S
G
E
E
V
V
I
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
S268
S
E
D
E
E
D
D
S
S
G
E
E
V
V
I
Dog
Lupus familis
XP_850477
699
75739
S25
S
E
D
E
D
D
D
S
S
G
E
E
V
V
I
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
S41
S
E
D
E
D
D
S
S
G
E
E
E
V
V
I
Rat
Rattus norvegicus
P13383
713
77129
S41
S
E
D
E
D
D
S
S
G
E
E
E
V
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
T21
K
K
G
A
A
A
A
T
P
G
K
K
A
M
A
Chicken
Gallus gallus
P15771
694
75622
P21
Q
K
K
M
A
P
P
P
K
K
V
E
E
S
E
Frog
Xenopus laevis
P20397
651
70177
S39
E
D
M
E
E
D
D
S
S
D
E
E
V
E
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
6.6
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
40
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
19
10
10
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
55
0
28
64
46
0
0
10
0
0
0
0
0
% D
% Glu:
10
55
0
64
37
0
0
0
0
19
64
73
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
19
46
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% I
% Lys:
10
19
10
0
0
0
0
0
10
10
10
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
10
10
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
55
0
0
0
0
0
19
64
46
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
64
55
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _