KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
17.27
Human Site:
S458
Identified Species:
38
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
S458
G
T
E
I
D
G
R
S
I
S
L
Y
Y
T
G
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
S730
G
T
E
I
D
G
R
S
I
S
L
Y
Y
T
G
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
S686
G
T
E
I
D
G
R
S
I
S
L
Y
Y
T
G
Dog
Lupus familis
XP_850477
699
75739
S447
G
T
E
I
D
G
R
S
I
S
L
Y
Y
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
R459
Q
G
A
E
I
D
G
R
S
V
S
L
Y
Y
T
Rat
Rattus norvegicus
P13383
713
77129
R461
Q
G
A
E
I
D
G
R
S
V
S
L
Y
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
I401
T
E
I
D
G
R
S
I
I
L
D
Y
T
G
E
Chicken
Gallus gallus
P15771
694
75622
V433
E
E
K
Q
G
T
E
V
D
G
R
A
M
V
I
Frog
Xenopus laevis
P20397
651
70177
S391
G
A
E
I
E
G
R
S
I
F
V
D
F
T
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
E213
V
K
R
K
K
T
E
E
S
S
E
E
E
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
Q227
S
Y
A
E
K
A
I
Q
E
M
Q
G
K
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
13.3
0
60
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
13.3
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
28
0
0
10
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
37
19
0
0
10
0
10
10
0
10
0
% D
% Glu:
10
19
46
28
10
0
19
10
10
0
10
10
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% F
% Gly:
46
19
0
0
19
46
19
0
0
10
0
10
0
10
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
46
19
0
10
10
55
0
0
0
0
0
19
% I
% Lys:
0
10
10
10
19
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
37
19
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
46
19
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
10
46
28
46
19
0
0
0
10
% S
% Thr:
10
37
0
0
0
19
0
0
0
0
0
0
10
46
19
% T
% Val:
10
0
0
0
0
0
0
10
0
19
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
46
55
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _